Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone
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Names | |
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Preferred IUPAC name
N-[4-(Trifluoromethoxy)phenyl]carbonohydrazonoyl dicyanide | |
Identifiers | |
3D model (JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.006.119 |
MeSH | FCCP |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C10H5F3N4O | |
Molar mass | 254.16811 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone (FCCP) is an ionophore that is a mobile ion carrier. It is referred to as an uncoupling agent because it disrupts ATP synthesis by transporting hydrogen ions through the mitochondrial membrane before they can be used to provide the energy for oxidative phosphorylation.[2] It is a nitrile and hydrazone. FCCP was first described in 1962 by Heytler.[3]
See also
References
- ^ FCCP - Compound Summary, PubChem.
- ^ MeSH Descriptor Data, MeSH.
- ^ Heytler, P G (1962). "A new class of uncoupling agents — Carbonyl cyanide phenylhydrazones". Biochemical and Biophysical Research Communications. 7 (4): 272–275. doi:10.1016/0006-291X(62)90189-4. PMID 13907155.
Categories:
- Chemical articles with multiple compound IDs
- Multiple chemicals in an infobox that need indexing
- Articles without KEGG source
- Articles with changed EBI identifier
- ECHA InfoCard ID from Wikidata
- Articles containing unverified chemical infoboxes
- Chembox image size set
- Articles with short description
- Short description matches Wikidata
- Ionophores
- Nitriles
- Trifluoromethyl ethers
- Uncouplers
- Hydrazones