Protein-coding gene in the species Homo sapiens
CTD small phosphatase-like protein is an enzyme that in humans is encoded by the CTDSPL gene .[5] [6] [7]
Interactions CTDSPL has been shown to interact with SNAI1 .[8]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000144677 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047409 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Ishikawa S, Kai M, Tamari M, Takei Y, Takeuchi K, Bandou H, Yamane Y, Ogawa M, Nakamura Y (Aug 1997). "Sequence analysis of a 685-kb genomic region on chromosome 3p22-p21.3 that is homozygously deleted in a lung carcinoma cell line" . DNA Res . 4 (1): 35–43. doi :10.1093/dnares/4.1.35 PMID 9179494 . ^ Protopopov A, Kashuba V, Zabarovska VI, Muravenko OV, Lerman MI, Klein G, Zabarovsky ER (Jan 2003). "An integrated physical and gene map of the 3.5-Mb chromosome 3p21.3 (AP20) region implicated in major human epithelial malignancies". Cancer Res . 63 (2): 404–12. PMID 12543795 . ^ "Entrez Gene: CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like" .^ Wu Y, Evers B Mark, Zhou Binhua P (Jan 2009). "Small C-terminal domain phosphatase enhances snail activity through dephosphorylation" . J. Biol. Chem . 284 (1). United States: 640–8. doi :10.1074/jbc.M806916200 ISSN 0021-9258 . PMC 2610500 PMID 19004823 .
Further reading
O'Keeffe B, Fong Y, Chen D, et al. (2000). "Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription" . J. Biol. Chem . 275 (1): 279–87. doi :10.1074/jbc.275.1.279 PMID 10617616 . Kim JB, Sharp PA (2001). "Positive transcription elongation factor B phosphorylates hSPT5 and RNA polymerase II carboxyl-terminal domain independently of cyclin-dependent kinase-activating kinase" . J. Biol. Chem . 276 (15): 12317–23. doi :10.1074/jbc.M010908200 PMID 11145967 . Ramanathan Y, Rajpara SM, Reza SM, et al. (2001). "Three RNA polymerase II carboxyl-terminal domain kinases display distinct substrate preferences" . J. Biol. Chem . 276 (14): 10913–20. doi :10.1074/jbc.M010975200 PMID 11278802 . Zhou M, Nekhai S, Bharucha DC, et al. (2002). "TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription" . J. Biol. Chem . 276 (48): 44633–40. doi :10.1074/jbc.M107466200 PMID 11572868 . Lin X, Taube R, Fujinaga K, Peterlin BM (2002). "P-TEFb containing cyclin K and Cdk9 can activate transcription via RNA" . J. Biol. Chem . 277 (19): 16873–8. doi :10.1074/jbc.M200117200 PMID 11884399 . Kim YK, Bourgeois CF, Isel C, et al. (2002). "Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation" . Mol. Cell. Biol . 22 (13): 4622–37. doi :10.1128/MCB.22.13.4622-4637.2002 . PMC 133925 PMID 12052871 . Yeo M, Lin PS, Dahmus ME, Gill GN (2003). "A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5" . J. Biol. Chem . 278 (28): 26078–85. doi :10.1074/jbc.M301791200 PMID 12721286 . Pinhero R, Liaw P, Bertens K, Yankulov K (2004). "Three cyclin-dependent kinases preferentially phosphorylate different parts of the C-terminal domain of the large subunit of RNA polymerase II" . Eur. J. Biochem . 271 (5): 1004–14. doi :10.1111/j.1432-1033.2004.04002.x PMID 15009212 . Kashuba VI, Li J, Wang F, et al. (2004). "RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies" . Proc. Natl. Acad. Sci. U.S.A . 101 (14): 4906–11. Bibcode :2004PNAS..101.4906K . doi :10.1073/pnas.0401238101 PMC 387347 PMID 15051889 .
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