CALCOCO1

CALCOCO1
Identifiers
Aliases	CALCOCO1, Cocoa, calphoglin, PP13275, calcium binding and coiled-coil domain 1
External IDs	MGI: 1914738 HomoloGene: 10845 GeneCards: CALCOCO1
Gene location (Human) Chr. Chromosome 12 (human) Band 12q13.13 Start 53,708,517 bp End 53,727,745 bp
Gene location (Mouse) Chr. Chromosome 15 (mouse) Band 15 F3|15 Start 102,615,212 bp End 102,630,613 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastric mucosa popliteal artery skin of abdomen right coronary artery ascending aorta right lung left coronary artery gastrocnemius muscle tibial nerve minor salivary glands Top expressed in ascending aorta lip aortic valve interventricular septum esophagus superior frontal gyrus skeletal muscle tissue secondary oocyte myocardium of ventricle thymus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function sequence-specific DNA binding beta-catenin binding transcription coactivator activity chromatin binding transcription coregulator activity protein C-terminus binding protein binding nuclear receptor coactivator activity armadillo repeat domain binding RNA polymerase II cis-regulatory region sequence-specific DNA binding Cellular component intracellular membrane-bounded organelle nucleus cytoplasm cytosol Biological process regulation of transcription, DNA-templated intracellular steroid hormone receptor signaling pathway Wnt signaling pathway transcription, DNA-templated positive regulation of transcription, DNA-templated signal transduction positive regulation of transcription by RNA polymerase II positive regulation of gene expression Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57658 67488 Ensembl ENSG00000012822 ENSMUSG00000023055 UniProt Q9P1Z2 Q8CGU1 RefSeq (mRNA) NM_001143682 NM_020898 NM_026192 RefSeq (protein) NP_001137154 NP_065949 NP_080468 Location (UCSC) Chr 12: 53.71 – 53.73 Mb Chr 15: 102.62 – 102.63 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Calcium-binding and coiled-coil domain-containing protein 1 is a protein that in humans is encoded by the CALCOCO1 gene.

External links

• Human CALCOCO1 genome location and CALCOCO1 gene details page in the UCSC Genome Browser.

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Lee SY, Obata Y, Yoshida M, et al. (2003). "Immunomic analysis of human sarcoma". Proc. Natl. Acad. Sci. U.S.A. 100 (5): 2651–6. Bibcode:2003PNAS..100.2651L. doi:10.1073/pnas.0437972100. PMC 151395. PMID 12601173.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Takahashi K, Inuzuka M, Ingi T (2005). "Cellular signaling mediated by calphoglin-induced activation of IPP and PGM". Biochem. Biophys. Res. Commun. 325 (1): 203–14. doi:10.1016/j.bbrc.2004.10.021. PMID 15522220.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Yang CK, Kim JH, Li H, Stallcup MR (2006). "Differential use of functional domains by CoCoA in its synergistic coactivator function with β-catenin or GRIP1". J. Biol. Chem. 281 (6): 3389–97. doi:10.1074/jbc.M510403200. PMC 1626527. PMID 16344550.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
• Yang CK, Kim JH, Stallcup MR (2007). "Role of the N-terminal activation domain of coactivator CoCoA in mediating transcriptional activation by β-catenin". Mol. Endocrinol. 20 (12): 3251–62. doi:10.1210/me.2006-0200. PMC 1770943. PMID 16931570.