Aristolochia fangchi

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Aristolochia fangchi
Scientific classification Edit this classification
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Magnoliids
Order: Piperales
Family: Aristolochiaceae
Genus: Aristolochia
Species:
A. fangchi
Binomial name
Aristolochia fangchi
Y.C.Wu ex L.D.Chow & S.M.Hwang
Synonyms[1]

Isotrema fangchi (Y.C.Wu ex L.D.Chow & S.M.Hwang) X.X.Zhu, S.Liao & J.S.Ma

Aristolochia fangchi (Chinese: 广防已 guang fang ji), is a species of flowering plant in the family Aristolochiaceae, native to Vietnam and southeast and south-central China.[1]

In 1993, a series of end-stage renal disease cases were reported from Belgium associated with a weight loss treatment, where Stephania tetrandra (Chinese: 粉防己 fen fang ji) in a herbal preparation was accidentally substituted with Aristolochia fangchi.[2][3] More than 105 patients were identified with nephropathy following the ingestion of this preparation from the same clinic from 1990 to 1992. Many required renal transplantation or dialysis.[4]

References

  1. ^ a b "Aristolochia fangchi Y.C.Wu ex L.D.Chow & S.M.Hwang". Plants of the World Online. Board of Trustees of the Royal Botanic Gardens, Kew. Retrieved 19 June 2021.
  2. ^ Vanherweghem, J.-L.; Tielemans, C.; Abramowicz, D.; Depierreux, M.; Vanhaelen-Fastre, R.; Vanhaelen, M.; Dratwa, M.; Richard, C.; Vandervelde, D.; Verbeelen, D.; Jadoul, M. (February 1993). "Rapidly progressive interstitial renal fibrosis in young women: association with slimming regimen including Chinese herbs". Lancet. 341 (8842): 387–91. doi:10.1016/0140-6736(93)92984-2. ISSN 0140-6736. PMID 8094166. S2CID 32428737.
  3. ^ Vanhaelen, Maurice; Vanhaelen-Fastre, Renée; But, Paul; Vanherweghem, Jean-Louis (January 1994). "Identification of aristolochic acid in Chinese herbs". The Lancet. 343 (8890): 174. doi:10.1016/S0140-6736(94)90964-4. ISSN 0140-6736. PMID 7904018. S2CID 34836561.
  4. ^ Li, X; Yang, L; Yu, Y (2001). "An analysis of the clinical and pathological characteristics of Mu-tong (a Chinese herb) induced tubulointerstitial nephropathy". Zhonghua Nei Ke Za Zhi. 40 (10): 681–7. PMID 11769723.


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