Anthocyanidin reductase

Anthocyanidin reductase
Identifiers
EC no.	1.3.1.77
CAS no.	93389-48-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

In enzymology, an anthocyanidin reductase (EC 1.3.1.77) is an enzyme that catalyzes the chemical reaction

a flavan-3-ol + 2 NAD(P)+ $\rightleftharpoons$ an anthocyanidin + 2 NAD(P)H + H⁺

The 3 substrates of this enzyme are flavan-3-ol, NAD⁺, and NADP⁺, whereas its 4 products are anthocyanidin, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is flavan-3-ol:NAD(P)+ oxidoreductase. Other names in common use include AtANR, and MtANR. This enzyme participates in flavonoid biosynthesis.

References

• Xie DY, Sharma SB, Paiva NL, Ferreira D, Dixon RA (2003). "Role of anthocyanidin reductase, encoded by BANYULS in plant flavonoid biosynthesis". Science. 299 (5605): 396–399. doi:10.1126/science.1078540. PMID 12532018.
• Xie DY, Sharma SB, Dixon RA (2004). "Anthocyanidin reductases from Medicago truncatula and Arabidopsis thaliana". Arch. Biochem. Biophys. 422 (1): 91–102. doi:10.1016/j.abb.2003.12.011. PMID 14725861.