Andrew G. Campbell

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Andrew Garrett Campbell
Alma materYork College, City University of New York
University of California, Los Angeles
Scientific career
InstitutionsBrown University
ThesisThe isolation and characterization of basement membrane components in Drosophila melanogaster (1987)

Andrew Garrett Campbell is an American biologist who is a professor of Medical Science and Dean of the Graduate School at Brown University. In 2020 he was named by Cell Press as one of the most 100 "inspiring Black scientists in America".[1]

Early life and education

Campbell studied biology at York College, City University of New York, minoring in French, and graduated in 1981. He moved to the West Coast of the United States for his graduate studies in the laboratory of John H. Fessler,[2] where he studied Drosophila melanogaster at the University of California, Los Angeles.[3] As a graduate student in 1986 Campbell partnered with fellow UCLA graduate student Theodore (Ted) B. Thederahn and UCLA graduate Robert B Laukka to serve as founding directors and principals of the Southern California-based research and radiation safety products manufacturing company, Bremshield Corporation whose products supported the U.S. academic biomedical research community and newly emerging biotech industry.[4] Campbell served as a postdoctoral fellow at both UCLA and the University of California, San Francisco.[5] As a postdoctoral Fellow in the laboratory of Dan S. Ray at UCLA, he began his studies of the endonuclease enzyme RNase H.[2] As a President's Postdoctoral Fellow at UCSF Campbell studied Hepatitis B Virus with William J. Rutter, founder of the Chiron Corporation which would go on to develop the Hepatitis B vaccine as the 1st genetically engineered vaccine to receive FDA approval for human use.

Research and career

In 1994 Campbell joined the faculty at Brown University as assistant professor of Medical Science. His research considers infectious microbial diseases in neglected populations and regions.[6] In particular, Campbell continued his studies of the endonuclease enzymes Ribonuclease H (RNases H), with which he hopes to better understand nucleic acid metabolic function.[7] He is also interested in the lifecycle of Trypanosoma brucei, a parasite carried by tsetse flies in sub-Saharan Africa.[8] Campbell is also interested in the role of viral RNase-H as therapeutic targets, and has investigated how mutations in RNase-H can give rise to drug resistance.[9]

Alongside his research, Campbell develops programs to improve the representation of historically underrepresented minority students in science and technology programs.[10][11] He was promoted to Dean of the Graduate School in 2016.[6][12] He is the fifteenth person to hold such a position. During his first two years as Graduate School Dean he increased diversity in the graduate student population to historic levels.[13] In 2019 he announced that Brown University would no longer require the Graduate Record Examination (GRE) to apply to 24 of Brown's 51 doctoral programs.[14]

Awards and honours

Selected publications

  • Olson, P F; Fessler, L I; Nelson, R E; Sterne, R E; Campbell, A G; Fessler, J H (April 1990). "Glutactin, a novel Drosophila basement membrane-related glycoprotein with sequence similarity to serine esterases". The EMBO Journal. 9 (4): 1219–1227. doi:10.1002/j.1460-2075.1990.tb08229.x. PMC 551798. PMID 2108864.
  • Akkina, RK; Rosenblatt, JD; Campbell, AG; Chen, IS; Zack, JA (1 September 1994). "Modeling human lymphoid precursor cell gene therapy in the SCID-hu mouse". Blood. 84 (5): 1393–1398. doi:10.1182/blood.V84.5.1393.1393. PMID 7520766.
  • Allen-Ramdial, Stacy-Ann A.; Campbell, Andrew G. (1 July 2014). "Reimagining the Pipeline: Advancing STEM Diversity, Persistence, and Success". BioScience. 64 (7): 612–618. doi:10.1093/biosci/biu076. PMC 4282132. PMID 25561747.
  • Estrada, Mica; Burnett, Myra; Campbell, Andrew G.; Campbell, Patricia B.; Denetclaw, Wilfred F.; Gutiérrez, Carlos G.; Hurtado, Sylvia; John, Gilbert H.; Matsui, John; McGee, Richard; Okpodu, Camellia Moses; Robinson, T. Joan; Summers, Michael F.; Werner-Washburne, Maggie; Zavala, MariaElena (1 September 2016). "Improving Underrepresented Minority Student Persistence in STEM". CBE: Life Sciences Education. 15 (3): es5. doi:10.1187/cbe.16-01-0038. PMC 5008901. PMID 27543633.

References

  1. ^ [1] Posted by Antentor O. Hinton Jr. | Published June 19, 2020, 12:40
  2. ^ a b Campbell, A. G.; Ray, D. S. (15 October 1993). "Functional complementation of an Escherichia coli ribonuclease H mutation by a cloned genomic fragment from the trypanosomatid Crithidia fasciculata". Proceedings of the National Academy of Sciences. 90 (20): 9350–9354. Bibcode:1993PNAS...90.9350C. doi:10.1073/pnas.90.20.9350. PMC 47565. PMID 8415705.
  3. ^ Campbell, Andrew Garrett (1987). The isolation and characterization of basement membrane components in Drosophila melanogaster (Thesis). OCLC 16261608.
  4. ^ https://businesssearch.sos.ca.gov/Document/RetrievePDF?Id=01546605-3778816
  5. ^ President's Postdoctoral Fellow at UCSF: [2]
  6. ^ a b c "Andrew G. Campbell | Graduate School". www.brown.edu. Retrieved 2021-01-01.
  7. ^ Campbell, Andrew G. (July 2001). "Expression of Moloney Murine Leukemia Virus RNase H Rescues the Growth Defect of an Escherichia coli Mutant". Journal of Virology. 75 (13): 6212–6217. doi:10.1128/JVI.75.13.6212-6217.2001. PMC 114339. PMID 11390625.
  8. ^ "Campbell, Andrew". vivo.brown.edu. Retrieved 2021-01-01.
  9. ^ Boyer, Paul L.; Smith, Steven J.; Zhao, Xue Zhi; Das, Kalyan; Gruber, Kevin; Arnold, Eddy; Burke, Terrence R.; Hughes, Stephen H. (July 2018). "Developing and Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase". Journal of Virology. 92 (13). doi:10.1128/JVI.02203-17. PMC 6002700. PMID 29643235.
  10. ^ December 1; Orenstein 401-863-1862, 2014 Media contact: David. "Why don't more minority students seek STEM careers? Ask them". news.brown.edu. Retrieved 2021-01-01.{{cite web}}: CS1 maint: numeric names: authors list (link)
  11. ^ Campbell, Andrew G.; Leibowitz, Michael J.; Murray, Sandra A.; Burgess, David; Denetclaw, Wilfred F.; Carrero-Martinez, Franklin A.; Asai, David J. (September 2013). "Partnered Research Experiences for Junior Faculty at Minority-Serving Institutions Enhance Professional Success". CBE: Life Sciences Education. 12 (3): 394–402. doi:10.1187/cbe.13-02-0025. PMC 3763007. PMID 24006388.
  12. ^ "Andrew G. Campbell, Ph.D. '87 |". Retrieved 2021-01-01.
  13. ^ With an eye on the world beyond Brown, Graduate School welcomes most diverse class to date
  14. ^ "Brown eliminates GRE test requirement for 24 doctoral programs". Brown University. Retrieved 2021-01-01.
  15. ^ "NSF Award Search: Award#9876299 - CAREER: Programmable Mobile Networking". nsf.gov. Retrieved 2021-01-01.
  16. ^ a b Chaiken, Jackson (2016-04-05). "Campbell named next dean of grad school". Brown Daily Herald. Retrieved 2021-01-01.
  17. ^ "ASCB Names 67 Society Fellows for 2017". ASCB. 2017-11-14. Retrieved 2021-01-01.
  18. ^ "Brown medical science, sociology faculty members elected AAAS fellows". Brown University. Retrieved 2021-01-01.
  19. ^ "Andrew G. Campbell of Brown University to Serve as Chair of CGS Board | Council of Graduate Schools". cgsnet.org. Retrieved 2021-01-01.
  20. ^ "Chalfie elected ASCB president for 2022". ASCB. 2020-05-09. Retrieved 2021-01-01.
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