Ameltolide
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Formula | C15H16N2O |
Molar mass | 240.306 g·mol−1 |
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Ameltolide, a 4-aminobenzamide derivative, is an experimental anticonvulsant agent, effective at inhibiting seizures in animal models.[1] It is non-toxic at dosing levels and no undesirable side effects are attributable to its application.[2]
References
- ^ Robertson DW, Beedle EE, Krushinski JH, Lawson RR, Parli CJ, Potts B, Leander JD (April 1991). "Synthesis and pharmacological evaluation of a major metabolite of ameltolide, a potent anticonvulsant". Journal of Medicinal Chemistry. 34 (4): 1253–7. doi:10.1021/jm00108a003. PMID 2016702.
- ^ Higdon GL, McKinley ER, Markham JK (July 1991). "Ameltolide. I: Developmental toxicology studies of a novel anticonvulsant". Teratology. 44 (1): 37–44. doi:10.1002/tera.1420440107. PMID 1957261.
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