Acetylenedicarboxylate decarboxylase
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| Acetylenedicarboxylate decarboxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.1.1.78 | ||||||||
| CAS no. | 72561-10-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme acetylenedicarboxylate decarboxylase (EC 4.1.1.78) catalyzes the chemical reaction
- acetylenedicarboxylate + H2O pyruvate + CO2
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is acetylenedicarboxylate carboxy-lyase (pyruvate-forming). Other names in common use include acetylenedicarboxylate hydratase, acetylenedicarboxylate hydrase, and acetylenedicarboxylate carboxy-lyase. This enzyme participates in pyruvate metabolism.
References
- Yamada EW, Jakoby WB (September 1958). "Enzymatic utilization of acetylenic compounds. I. An enzyme converting acetylenedicarboxylic acid to pyruvate". The Journal of Biological Chemistry. 233 (3): 706–11. PMID 13575441.
