Protein-coding gene in the species Homo sapiens
Acyl-CoA Synthetase, Bubblegum Family, member 1 (ACSBG1) is an enzyme that in humans is encoded by the ACSBG1 gene .[5] [6] [7]
The protein encoded by this gene possesses long-chain acyl -CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis .[7] [8]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000103740 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032281 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro" . DNA Res . 5 (3): 169–76. doi :10.1093/dnares/5.3.169 PMID 9734811 . ^ Steinberg SJ, Morgenthaler J, Heinzer AK, Smith KD, Watkins PA (Nov 2000). "Very long-chain acyl-CoA synthetases. Human "bubblegum" represents a new family of proteins capable of activating very long-chain fatty acids" . J Biol Chem . 275 (45): 35162–9. doi :10.1074/jbc.M006403200 PMID 10954726 . ^ a b "Entrez Gene: ACSBG1 acyl-CoA synthetase bubblegum family member 1" .^ Moriya-Sato A, et al. (Dec 2000). "Novel acyl-CoA synthetase in adrenoleukodystrophy target tissues". Biochem Biophys Res Commun . 279 (1): 62–8. doi :10.1006/bbrc.2000.3897 . PMID 11112418 .
External links Further reading
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem . 236 (1): 107–13. doi :10.1006/abio.1996.0138 . PMID 8619474 . Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing" . Genome Res . 7 (4): 353–8. doi :10.1101/gr.7.4.353 . PMC 139146 PMID 9110174 . Moriya-Sato A, Hida A, Inagawa-Ogashiwa M, et al. (2001). "Novel acyl-CoA synthetase in adrenoleukodystrophy target tissues". Biochem. Biophys. Res. Commun . 279 (1): 62–8. doi :10.1006/bbrc.2000.3897 . PMID 11112418 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Pei Z, Oey NA, Zuidervaart MM, et al. (2004). "The acyl-CoA synthetase "bubblegum" (lipidosin): further characterization and role in neuronal fatty acid beta-oxidation." J. Biol. Chem . 278 (47): 47070–8. doi :10.1074/jbc.M310075200 PMID 12975357 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Asheuer M, Bieche I, Laurendeau I, et al. (2005). "Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy" . Hum. Mol. Genet . 14 (10): 1293–303. doi :10.1093/hmg/ddi140 PMID 15800013 .
