4-methyleneglutaminase

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4-methyleneglutaminase
Identifiers
EC no.3.5.1.67
CAS no.86855-36-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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Gene OntologyAmiGO / QuickGO
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In enzymology, a 4-methyleneglutaminase (EC 3.5.1.67) is an enzyme that catalyzes the chemical reaction

4-methylene-L-glutamine + H2O 4-methylene-L-glutamate + NH3

Thus, the two substrates of this enzyme are 4-methylene-L-glutamine and H2O, whereas its two products are 4-methylene-L-glutamate and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is 4-methylene-L-glutamine amidohydrolase. Other names in common use include 4-methyleneglutamine deamidase, and 4-methyleneglutamine amidohydrolase. This enzyme participates in c5-branched dibasic acid metabolism.

References

  • Ibrahim SA, Lea PJ, Fowden L (1984). "Preparation and properties of 4-methyleneglutaminase from the leaves of peanut (Arachis hypogaea)". Phytochemistry. 23 (8): 1545–1549. doi:10.1016/S0031-9422(00)83436-6.