1-alpha-O-Galloylpunicalagin

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1-α-O-Galloylpunicalagin
Chemical structure of 1-α-O-galloylpunicalagin
Names
Other names
Combreglutinin
Teroblongin
Identifiers
Properties
C55H32O34
Molar mass 1236.827 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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1-α-O-Galloylpunicalagin is an ester of gallic acid and punicalagin, a type of ellagitannin. It is found in the pomegranate (Punica granatum) and in Combretum glutinosum.[1]

A study in Taiwan showed that 1-α-O-galloylpunicalagin induced nitric oxide production in a dose-dependent manner in endothelial cells via the PI3K/AKT/mTOR pathway.[2]

References

  1. ^ Combreglutinin, a Hydrolyzable Tannin from Combretum glutinosum. Akino Jossang, Jean-Louis Pousset and Bernard Bodo, J. Nat. Prod., 1994, volume 57, issue 6, pages 732–737, doi:10.1021/np50108a008
  2. ^ Chen, LG; Liu, YC; Hsieh, CW; Liao, BC; Wung, BS (2008). "Tannin 1-alpha-O-galloylpunicalagin induces the calcium-dependent activation of endothelial nitric-oxide synthase via the phosphatidylinositol 3-kinase/Akt pathway in endothelial cells". Molecular Nutrition & Food Research. 52 (10): 1162–71. doi:10.1002/mnfr.200700335. PMID 18435486.
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