Protein-coding gene in the species Homo sapiens
Transcription initiation protein SPT3 homolog is a protein that in humans is encoded by the SUPT3H gene .[5] [6] [7]
Interactions Transcription initiation protein SPT3 homolog has been shown to interact with GCN5L2 ,[8] [9] TAF6L ,[9] TADA3L ,[9] TAF5L ,[9] SF3B3 ,[9] SUPT7L ,[9] Myc ,[10] TAF9 ,[9] Transformation/transcription domain-associated protein ,[9] TAF12 ,[9] TAF10 ,[8] [9] TAF4 [8] DDB1 .[9]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000196284 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038954 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Ogryzko VV, Kotani T, Zhang X, Schiltz RL, Howard T, Yang XJ, Howard BH, Qin J, Nakatani Y (Jul 1998). "Histone-like TAFs within the PCAF histone acetylase complex" . Cell . 94 (1): 35–44. doi :10.1016/S0092-8674(00)81219-2 PMID 9674425 . S2CID 18942972 . ^ Martinez E, Kundu TK, Fu J, Roeder RG (Sep 1998). "A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID" . The Journal of Biological Chemistry . 273 (37): 23781–5. doi :10.1074/jbc.273.37.23781 PMID 9726987 . ^ "Entrez Gene: SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)" .^ a b c Brand M, Moggs JG, Oulad-Abdelghani M, Lejeune F, Dilworth FJ, Stevenin J, Almouzni G, Tora L (Jun 2001). "UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation" . The EMBO Journal . 20 (12): 3187–96. doi :10.1093/emboj/20.12.3187 . PMC 150203 PMID 11406595 . ^ a b c d e f g h i j k Martinez E, Palhan VB, Tjernberg A, Lymar ES, Gamper AM, Kundu TK, Chait BT, Roeder RG (Oct 2001). "Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo" . Molecular and Cellular Biology . 21 (20): 6782–95. doi :10.1128/MCB.21.20.6782-6795.2001 . PMC 99856 PMID 11564863 . ^ Liu X, Tesfai J, Evrard YA, Dent SY, Martinez E (May 2003). "c-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activation" . The Journal of Biological Chemistry . 278 (22): 20405–12. doi :10.1074/jbc.M211795200 PMC 4031917 PMID 12660246 .
Further reading
Yu J, Madison JM, Mundlos S, Winston F, Olsen BR (Oct 1998). "Characterization of a human homologue of the Saccharomyces cerevisiae transcription factor spt3 (SUPT3H)". Genomics . 53 (1): 90–6. doi :10.1006/geno.1998.5500 . PMID 9787080 . Vassilev A, Yamauchi J, Kotani T, Prives C, Avantaggiati ML, Qin J, Nakatani Y (Dec 1998). "The 400 kDa subunit of the PCAF histone acetylase complex belongs to the ATM superfamily" . Molecular Cell . 2 (6): 869–75. doi :10.1016/S1097-2765(00)80301-9 PMID 9885574 . Brand M, Yamamoto K, Staub A, Tora L (Jun 1999). "Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction" . The Journal of Biological Chemistry . 274 (26): 18285–9. doi :10.1074/jbc.274.26.18285 PMID 10373431 . Speek M (Mar 2001). "Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes" . Molecular and Cellular Biology . 21 (6): 1973–85. doi :10.1128/MCB.21.6.1973-1985.2001 . PMC 86790 PMID 11238933 . Brand M, Moggs JG, Oulad-Abdelghani M, Lejeune F, Dilworth FJ, Stevenin J, Almouzni G, Tora L (Jun 2001). "UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation" . The EMBO Journal . 20 (12): 3187–96. doi :10.1093/emboj/20.12.3187 . PMC 150203 PMID 11406595 . Martinez E, Palhan VB, Tjernberg A, Lymar ES, Gamper AM, Kundu TK, Chait BT, Roeder RG (Oct 2001). "Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo" . Molecular and Cellular Biology . 21 (20): 6782–95. doi :10.1128/MCB.21.20.6782-6795.2001 . PMC 99856 PMID 11564863 . Cavusoglu N, Brand M, Tora L, Van Dorsselaer A (Feb 2003). "Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis". Proteomics . 3 (2): 217–23. doi :10.1002/pmic.200390030 . PMID 12601814 . S2CID 6035986 . Liu X, Tesfai J, Evrard YA, Dent SY, Martinez E (May 2003). "c-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activation" . The Journal of Biological Chemistry . 278 (22): 20405–12. doi :10.1074/jbc.M211795200 PMC 4031917 PMID 12660246 . 
