Proteins produced and secreted by the liver

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The liver plays the major role in producing proteins that are secreted into the blood, including major plasma proteins, factors in hemostasis and fibrinolysis, carrier proteins, hormones, prohormones and apolipoprotein:

Major plasma proteins

All plasma proteins except Gamma-globulins are synthesised in the liver.[1]

Factors in hemostasis and fibrinolysis

Carrier proteins

Hormones

Prohormones

  • Angiotensinogen, when converted to angiotensin causes vasoconstriction and release of aldosterone, in effect increasing blood pressure

Apolipoproteins

References

General reference for the list of included substances (but not their functions):

  • Table 45–4 in: Walter F., PhD. Boron (2003). Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. p. 1300. ISBN 1-4160-2328-3.

Other:

  1. ^ Miller, L. L.; Bale, W. F. (February 1954). "Synthesis of all plasma protein fractions except gamma globulins by the liver; the use of zone electrophoresis and lysine-epsilon-C14 to define the plasma proteins synthesized by the isolated perfused liver". The Journal of Experimental Medicine. 99 (2): 125–132. doi:10.1084/jem.99.2.125. ISSN 0022-1007. PMC 2180344. PMID 13130789.
  2. ^ Lippincott's Illustrated Reviews: Immunology. Paperback: 384 pages. Publisher: Lippincott Williams & Wilkins; (July 1, 2007). Language: English. ISBN 978-0-7817-9543-2. Page 182
  3. ^ BRS Pathology 5th Edition, pg. 196
  4. ^ Robbins Basic Pathology 9th Edition, Chapter 11