L-Sorbose 1-dehydrogenase

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L-sorbose 1-dehydrogenase
Identifiers
EC no.1.1.99.32
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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NCBIproteins

L-Sorbose 1-dehydrogenase (EC 1.1.99.32, SDH) is an enzyme with systematic name L-sorbose:acceptor 1-oxidoreductase.[1] This enzyme catalyses the following chemical reaction

L-sorbose + acceptor 1-dehydro-L-sorbose + reduced acceptor

The product, L-sorbosone, is an intermediate in bacterial 2-keto-L-gulonic-acid formation. Co2+ stimulate activity of this membrane-bound enzyme, while Cu2+ act as an inhibitor.

References

  1. ^ Sugisawa T, Hoshino T, Nomura S, Fujiwara A (1991). "Isolation and characterization of membrane-bound L-sorbose dehydrogenase from Gluconobacter melanogenus UV10". Agric. Biol. Chem. 55: 363–370. doi:10.1271/bbb1961.55.363.

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