File:Topo IA catalytic cycle Illustration.png
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Summary
| Description |
English: Strand-passage mechanism for type IA topos. (1) Topo binds the G-segment ssDNA region, (2) the G-segment is cleaved. (3) The topo DNA gate is opened, (4) which allows T-segment transfer through the cleaved G-strand. (5) The DNA gate is closed, (6) and the G-strand is re-ligated, changing the linking number by 1. (7) The topo can then go through another round of relaxation or dissociate from the DNA. Type IA topo (domains 1-4) is in pink, the active site tyrosine is yellow and the DNA is grey. |
| Date | |
| Source | Own work |
| Author | Kcneuman |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 06:24, 10 April 2022 | | 2,366 × 1,906 (724 KB) | commons>Kcneuman | Uploaded own work with UploadWizard |
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