File:Proteolysis targeting chimera mechanism.svg

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Description Proteolysis targeting chimera mechanism. E1, E2, E3: ubiquitination enzymes; Ub = ubiquitin; PROTAC = proteolysis targeting chimera; target = protein to be degraded
Date
Source Own work, based on Ishoey, Mette (2018). "Translation Termination Factor GSPT1 is a Phenotypically Relevant Off-Target of Heterobifunctional Phthalimide Degraders". ACS Chemical Biology 13 (3): 553–560. DOI:10.1021/acschembio.7b00969. PMID 29356495.
Author Anypodetos

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20 June 2021

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current13:40, 20 June 2021Thumbnail for version as of 13:40, 20 June 20211,964 × 602 (17 KB)commons>Anypodetos{{Information |Description={{w|Proteolysis targeting chimera}} mechanism. E1, E2, E3: ubiquitination enzymes; Ub = ubiquitin; PROTAC = proteolysis targeting chimera; target = protein to be degraded |Source={{own}} |Date=2021-06-20 |Author= Anypodetos |Permission= |other_versions= }} Category:Mechanism of action

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