File:PMC4387477 jcn-11-122-g001.png

English: Summary of the proposed targets for DBS in Tourette syndrome. A: The thalamus in a coronal view, wherein the centromedian-parafascicular (CM-pf) complex is targeted. B: A cross-sectional view of the thalamus in detail, demonstrating the anatomical relation of the CM nucleus with the anterior portion of the ventralis oralis (VOA) nucleus, targeted by additional coagulations during the initial thalamotomy studies. C: Different areas of globus pallidus interna (GPi) that have been targeted, and D: A less studied, although with some reports of satisfactory clinical response, the anterior limb of internal capsule (AIC) and nucleus accumbens (NA). DBS: deep brain stimulation, GPe: globus palidus externa, SN: substantia nigra pars reticulata, STN: subthalamic nucleus, VOP: posterior portion of the ventralis oralis.