File:PMC3068525 431 2011 1396 Fig1 HTML (1).png

English: Fig1: Photographs highlighting several important clinical features from four classical syndromic PID, which can be diagnosed by cytogenetic studies. (a-1, a-2) Ataxia telangiectasia: note the conjunctival telangiectasias and the rather expressionless facies; (b) Nijmegen breakage syndrome: note the microcephaly, the prominent midface with long nose and long philtrum, receding mandible, large ears, and sparse hair; (c) Bloom syndrome: note the butterfly rash on the cheeks; (d) ICF syndrome: note the epicanthic folds, flat broad nasal bridge with ocular hypertelorism, and low-set ears