File:PMC2569912 1750-1172-3-25-2 (1).png

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PMC2569912_1750-1172-3-25-2_(1).png(183 × 246 pixels, file size: 25 KB, MIME type: image/png)

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Attribution 2.0 Generic (CC BY 2.0)

Summary

Author:Ferri C, Dipartimento Medicine e Specialità Mediche, Cattedra ed U,O,C, di Reumatologia, Università di Modena & Reggio Emilia, Modena(Openi/ National Library of Medicine) Source:https://openi.nlm.nih.gov/detailedresult?img=PMC2569912_1750-1172-3-25-2&query=&req=4 Description:F2: Cutaneous manifestations of mixed cryoglobulinemia (MC). (a) recent onset orthostatic purpura; at this stage the histopathological evaluation shows (b) the classical necrotizing leukocytoclastic vasculitis characterized by diffuse fibrinoid necrosis and disintegrated neutrophil permeation of the vessel walls; (c) symmetrical hyperpigmentation of the skin on the legs after repeated episodes of purpura; both orthostatic purpura and these permanent ochraceous lesions represent the typical skin manifestations of MC; (d) severe vasculitic manifestation; (e) wide skin ulcer, often resistant to treatment.(cropped version per permission via license)

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Date/TimeThumbnailDimensionsUserComment
current16:44, 26 March 2022Thumbnail for version as of 16:44, 26 March 2022183 × 246 (25 KB)Ozzie10aaaaAuthor:Ferri C, Dipartimento Medicine e Specialità Mediche, Cattedra ed U,O,C, di Reumatologia, Università di Modena & Reggio Emilia, Modena(Openi/ National Library of Medicine) Source:https://openi.nlm.nih.gov/detailedresult?img=PMC2569912_1750-1172-3-25-2&query=&req=4 Description:F2: Cutaneous manifestations of mixed cryoglobulinemia (MC). (a) recent onset orthostatic purpura; at this stage the histopathological evaluation shows (b) the classical necrotizing leukocytoclastic vasculitis ch...

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