File:Imr12466-fig-0006-m.png

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Imr12466-fig-0006-m.png ‎(500 × 285 pixels, file size: 100 KB, MIME type: image/png)

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Description
English: Properdin functions. Properdin (P) enhances alternative pathway activity in one of two ways: (1) acting as a positive regulator of pre-existing alternative pathway activity or (2) initiating alternative pathway activity. Properdin acts as a positive regulator by stabilizing the alternative pathway C3 and C5 convertases, increasing their activity 5- to 10-fold. As a pattern recognition molecule, properdin binds selectively to specific surfaces upon which it recruits C3b or C3(H2O) to initiate alternative pathway activity
Date
Source https://onlinelibrary.wiley.com/doi/10.1111/imr.12466
Author Adam Z. Blatt, Sabina Pathan, Viviana P. Ferreira

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Properdin deficiency

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current21:14, 24 October 2023Thumbnail for version as of 21:14, 24 October 2023500 × 285 (100 KB)commons>Ozzie10aaaaUploaded a work by Adam Z. Blatt, Sabina Pathan, Viviana P. Ferreira from https://onlinelibrary.wiley.com/doi/10.1111/imr.12466 with UploadWizard

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