File:Hhhs-Image001.jpg

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Hhhs-Image001.jpg ‎(641 × 436 pixels, file size: 74 KB, MIME type: image/jpeg)

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Summary

Description
English: Compartmentalization of the biochemical pathways involved in HHH syndrome as a result of deficiency of the mitochondrial ornithine transporter (ORNT1; encoded by SLC25A15), leading to abnormal accumulation of the metabolites shown in black-framed rectangles. The urea cycle proteins are mostly expressed in the periportal hepatocytes of the liver, whereas the proteins of the ornithine degradation pathway are expressed in the pericentral hepatocytes and other tissues including the brain, liver, or heart and cell types including fibroblasts, astrocytes, and lymphocytes.
Date
Source https://www.ncbi.nlm.nih.gov/books/NBK97260/figure/hhhs.F1/?_ga=2.8177211.82893564.1688421856-1434259302.1688161770
Author Jose Camacho, and Natalia Rioseco-Camacho,

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English: This file is licensed CC BY-NC 3.0

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current20:34, 4 July 2023Thumbnail for version as of 20:34, 4 July 2023641 × 436 (74 KB)Ozzie10aaaaUploaded a work by Jose Camacho, and Natalia Rioseco-Camacho, from https://www.ncbi.nlm.nih.gov/books/NBK97260/figure/hhhs.F1/?_ga=2.8177211.82893564.1688421856-1434259302.1688161770 with UploadWizard

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