File:Hedgehog signalling copy.svg
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Size of this PNG preview of this SVG file: 602 × 595 pixels. Other resolutions: 243 × 240 pixels | 486 × 480 pixels | 777 × 768 pixels | 1,036 × 1,024 pixels | 2,072 × 2,048 pixels.
Original file (SVG file, nominally 602 × 595 pixels, file size: 578 KB)
Summary
| Description |
English: Suggested pathway of Smoothened(Smo) regulation via Hedgehog (Hh) and Patched (Ptch1)
When the Hedgehog protein (Hh) is not present (A.), the transmembrane Patched (Ptch1) removes oxysterols, thus preventing them from interacting with the transmembrane protein Smoothened (Smo). When Hh is bound to Ptch1 (B.), Ptch1 no longer removes oxysterols; oxysterols accumulate and activate Smo, allowing it's signalling other cellular pathways. Inspired by diagrams created by Cyclopamine |
| Date | |
| Source | Own work |
| Author | Adenosine |
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File history
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 21:06, 30 June 2009 | | 602 × 595 (578 KB) | commons>Adenosine | {{Information |Description={{en|1=''Suggested pathway of Smoothened(Smo) regulation via Hedgehog (Hh) and Patched (Ptch1)'' When the Hedgehog protein (Hh) is not present (A.), the transmembrane Patched (Ptch1) removes [[w:oxysterol|oxysterols] |
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