File:GPCR activation.jpg

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current06:31, 21 June 2010Thumbnail for version as of 06:31, 21 June 20101,667 × 1,667 (428 KB)commons>Repapetilto~commonswiki{{Information |Description={{en|1=Cartoon of GPCR Conformational Activation. Ligand binding disrupts an ionic lock between the E/DRY motif of TM-3 and acidic residues of TM-6. As a result the GPCR reorganizes to allow activation of G-alpha proteins. The s

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