File:Bupropion bioequivalency comparison.svg

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Summary

Description A bioequivalency profile comparison of extended-release bupropion as produced by Impax Laboratories for Teva and Biovail for GlaxoSmithKline.
Note: The generic drug illustrated in this graphic was not affected by the FDA's 300 mg recall and is still available in the United States as of April 2013.[1][2]
Date
Source Own work based on FDA data [3]
Author CMBJ

Licensing

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See also

Notes

  1. ↑ (2012-10-03). "FDA Update: Budeprion XL 300 mg Not Therapeutically Equivalent to Wellbutrin XL 300 mg". Food and Drug Administration. Retrieved on 2013-04-29.
  2. ↑ Moeller, Karen E.. "Wellbutrin/Budeprion XL 300 mg". NAMI. Retrieved on 2013-04-28.
  3. ↑
    Time
    (hours)         		Mean plasma concentration, Impax
    (ng/mL)         		Mean plasma concentration, Biovail
    (ng/mL)
    0 0 0
    0.5 5 1
    1 31.5 6.5
    1.5 51 15
    2 62 19.5
    3 60 28
    4 53 46
    5 48 67
    6 38 51.5
    7 33 46
    8 29 39
    10 24 28.5
    12 20 23.5
    16 12 13.5
    24 6.5 8
    Data derived from FDA graphic chart.

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28 April 2013

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current08:59, 29 April 2013Thumbnail for version as of 08:59, 29 April 20131,000 × 650 (260 KB)commons>CMBJ

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