File:Bicalutamide levels as a function of dosage in men.png

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English: I made this, anyone can use it. Created from source material using Plotly.

Steady-state plasma levels of (R)-bicalutamide as a function of bicalutamide dosage in men. Demonstrates the linearity of bicalutamide absorption across dosages of 10 to 600 mg/day.

Sources of the values:

  • (1998). "Casodex 10-200 mg daily, used as monotherapy for the treatment of patients with advanced prostate cancer. An overview of the efficacy, tolerability and pharmacokinetics from three phase II dose-ranging studies. Casodex Study Group". Eur. Urol. 33 (1): 39–53. DOI:10.1159/000019526. PMID 9471040.
  • (2006). "Tolerability, efficacy and pharmacokinetics of bicalutamide 300 mg, 450 mg or 600 mg as monotherapy for patients with locally advanced or metastatic prostate cancer, compared with castration". BJU Int. 98 (3): 563–72. DOI:10.1111/j.1464-410X.2006.06275.x. PMID 16771791.
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Author Medgirl131

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