File:41436 2020 942 Fig2 HTML.webp

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41436_2020_942_Fig2_HTML.webp(685 × 283 pixels, file size: 46 KB, MIME type: image/webp)

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Summary

Description
English: (a) The three-dimensional structure of human GALK1 is shown in green. Adenosine triphosphate (ATP) (cyan) and galactose (hot pink) are shown bound in the active site. The two affected residues are shown: Asp46 (orange) and Thr352 (yellow). (b) A close-up of the active site showing how Asp46 binds, and helps orientate, the galactose molecule through C3-OH and C4-OH. The structure is based on PDB: 1WUU with gaps filled, selenomethionines converted to methionines, and AMP; PNP to ATP.5,40 Images created with PyMol.
Date N/A
Source https://www.nature.com/articles/s41436-020-00942-9
Author M. Estela Rubio-Gozalbo , Britt Derks , Anibh Martin Das , Uta Meyer , Dorothea Möslinger , M. Luz Couce , Aurélie Empain , Can Ficicioglu , Natalia Juliá Palacios , Mariela M. De Los Santos De Pelegrin, Isabel A. Rivera , Sabine Scholl-Bürgi , Annet M. Bosch, David Cassiman , Didem Demirbas , Matthias Gautschi , Ina Knerr , Philippe Labrune , Anastasia Skouma , Patrick Verloo , Saskia B. Wortmann , Eileen P. Treacy, David J. Timson & Gerard T. Berry

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English: This file is licensed CC BY-NC-ND 4.0

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Date/TimeThumbnailDimensionsUserComment
current00:53, 19 November 2023Thumbnail for version as of 00:53, 19 November 2023685 × 283 (46 KB)Ozzie10aaaaUploaded a work by M. Estela Rubio-Gozalbo , Britt Derks , Anibh Martin Das , Uta Meyer , Dorothea Möslinger , M. Luz Couce , Aurélie Empain , Can Ficicioglu , Natalia Juliá Palacios , Mariela M. De Los Santos De Pelegrin, Isabel A. Rivera , Sabine Scholl-Bürgi , Annet M. Bosch, David Cassiman , Didem Demirbas , Matthias Gautschi , Ina Knerr , Philippe Labrune , Anastasia Skouma , Patrick Verloo , Saskia B. Wortmann , Eileen P. Treacy, David J. Timson & Gerard T. Berry from https://www.natur...

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