File:13311 2018 674 Fig3 HTML (1)-Photoroom.jpg

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13311_2018_674_Fig3_HTML_(1)-Photoroom.jpg ‎(685 × 400 pixels, file size: 39 KB, MIME type: image/jpeg)

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Summary

Description
English: Routes to treatment. Schematic depicts the mitochondrial targets of treatments currently being tested for use in treating mitochondrial myopathy. A wide range of approaches are currently in use including the targeting of mitochondrial biogenesis (bezafibrate, RTA-408, exercise, acipimox and nicotinamide riboside), oxidative phosphorylation (CoQ10, idebenone, riboflavin and thiamine), ROS (RTA-498, KH176, CoQ10, idebenone), increasing NAD+ (acipimox and nicotinamide riboside), mtDNA gene editing (mitochondrial TALENS and zinc finger nucleases), lipid utilization (ketogenic diet), and cardiolipin stabilization (elamipretide)
Date
Source https://link.springer.com/article/10.1007/s13311-018-00674-4
Author Syeda T. Ahmed, Lyndsey Craven, Oliver M. Russell, Doug M. Turnbull & Amy E. Vincent

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idebenone

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current22:05, 13 April 2024Thumbnail for version as of 22:05, 13 April 2024685 × 400 (39 KB)commons>Ozzie10aaaaUploaded a work by Syeda T. Ahmed, Lyndsey Craven, Oliver M. Russell, Doug M. Turnbull & Amy E. Vincent from https://link.springer.com/article/10.1007/s13311-018-00674-4 with UploadWizard

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