File:1-s2.0-S1930043323001425-gr3.jpg

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1-s2.0-S1930043323001425-gr3.jpg ‎(670 × 439 pixels, file size: 72 KB, MIME type: image/jpeg)

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Description
English: Fig. 3. Graphical illustration of the downstream mechanism of Stx-induced endothelial injury in brain blood vessels. TNF induces Gb3 upregulation by endothelial cells, which subsequently increases the affinity of these cells to Stx (1). Stx effect on endothelial cells involves a DNA damage response (2), which results in the activation of caspase enzymes (3) with subsequent apoptosis (4). Stx: shiga toxin, TNF: tumor necrosis factor, Gb3: globotriaosylceramide.
Date
Source https://www.sciencedirect.com/science/article/pii/S1930043323001425
Author Mansour MA, Khalil DF, Hasham MA, Youssef A, Rashad M, Awadallah M, Ali H.

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current00:07, 11 April 2024Thumbnail for version as of 00:07, 11 April 2024670 × 439 (72 KB)Ozzie10aaaaUploaded a work by Mansour MA, Khalil DF, Hasham MA, Youssef A, Rashad M, Awadallah M, Ali H. from https://www.sciencedirect.com/science/article/pii/S1930043323001425 with UploadWizard

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