PD 144418
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Chemical and physical data | |
Formula | C18H22N2O |
Molar mass | 282.387 g·mol−1 |
3D model (JSmol) | |
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PD 144418 or 1,2,3,6-tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine is a potent and selective ligand for the sigma-1 receptor, with a reported binding affinity of Ki = 0.08 ± 0.01 nM, and 17 212 times selectivity over the sigma-2 receptor.[1]
References
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