DiOC6
Jump to navigation
Jump to search
![]() | |
Names | |
---|---|
IUPAC name
3-Hexyl-2-[3-(3-hexyl-2(3H)benzoxazolylidene)-1-propenyl]benzoxazolium iodide
| |
Other names
3,3′-Dihexyloxacarbocyanine iodide
| |
Identifiers | |
3D model (JSmol)
|
|
ChemSpider | |
ECHA InfoCard | 100.155.178 |
PubChem CID
|
|
UNII | |
CompTox Dashboard (EPA)
|
|
| |
| |
Properties | |
C29H37IN2O2 | |
Molar mass | 572.531 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
DiOC6 (3,3′-dihexyloxacarbocyanine iodide) is a fluorescent dye used for the staining of a cell's endoplasmic reticulum,[2] vesicle membranes and mitochondria.[3] Binding to these structures occurs via the dye's hydrophilic groups. DiOC6 can be used to label living cells, however they are quickly damaged due to the dye's extreme phototoxicity, so cells stained with this dye can only be exposed to light for short periods of time. When exposed to blue light, the dye fluoresces green.
See also
References
- ^ 3,3′-Dihexyloxacarbocyanine iodide at Sigma-Aldrich
- ^ Terasaki M. (1989). "Fluorescent labeling of endoplasmic reticulum". Methods Cell Biol. 29: 125–35. doi:10.1016/s0091-679x(08)60191-0. PMID 2643757.
- ^ Koning AJ; et al. (1993). "DiOC6 staining reveals organelle structure and dynamics in living yeast cells". Cell Motil Cytoskeleton. 25 (2): 111–28. doi:10.1002/cm.970250202. PMID 7686821.
Categories:
- Articles without EBI source
- Articles without KEGG source
- Articles with changed ChemSpider identifier
- ECHA InfoCard ID from Wikidata
- Articles with changed InChI identifier
- Articles containing unverified chemical infoboxes
- Chembox image size set
- Articles with short description
- Short description matches Wikidata
- Cyanine dyes
- Vital stains
- Benzoxazoles
- Quaternary ammonium compounds
- All stub articles
- Organic compound stubs