WikiProjectMed:Vaccine

From WikiProjectMed
Jump to navigation Jump to search

There are claims that certain folks cannot be vaccinated against COVID19. Still trying figure out who truly cannot be vaccinated... Yes there are people who have difficulty accessing vaccines but this is not a contraindication.

Pregnancy and breastfeeding

Green checkmarkY "mRNA COVID-19 vaccines are safe for people who are pregnant or breastfeeding" Public Health Agency of Canada.[1]

Guillain Barre

Green checkmarkY "People who have previously had GBS may receive a COVID-19 vaccine. To date, no cases of GBS have been reported following vaccination in participants in the mRNA COVID-19 vaccine clinical trials." CDC[2]

Rheumatologic disorders

Green checkmarkY "Rheumatology patients being actively treated with immunosuppressive medications [should] receive a third dose of the Pfizer-BioNTech or Moderna mRNA COVID-19 vaccines".[3]

Compromised immune systems

Green checkmarkY "People with moderately to severely compromised immune systems should receive an additional dose of mRNA COVID-19 vaccine after the initial 2 doses." This includes people with HIV/AIDS. CDC[2]

Bell palsy

Green checkmarkY "People who have previously had Bell’s palsy may receive a COVID-19 vaccine". CDC[2]

Allergies

Anaphylaxis

Green checkmarkY "CDC recommends that people get vaccinated even if they have a history of severe allergic reactions not related to vaccines or injectable medications"[4] Health Canada states "Individuals with proven severe allergic reaction (e.g., anaphylaxis) to injectable therapy not related to a component of authorized COVID-19 vaccines (e.g. intramuscular, intravenous, or subcutaneous vaccines or therapies) may be routinely vaccinated and do not need to be assessed."[5] An extended period of 30 minutes of observation should be provided.[5] Idiopathic anaphylaxis is not a contraindication to any of the vaccines.[6]

Even if someone has allergies including anaphylaxis to the first dose of an mRNA one trial found "all 159 patients, including 19 individuals with first-dose anaphylaxis, tolerated the second dose".[7]

PEG

checkY For those with a severe PEG allergy, mRNA vaccines are not to be used.[4][5][8] There have been a total of 37 documented cases of PEG allergies from 1977 to 2016, of which 28 were severe.[9] "Individuals with suspected but unproven allergy to a vaccine component (e.g. PEG) may be routinely vaccinated and do not need a specific assessment regarding this suspected allergy."[5]

"Vaccination may be considered in individuals with mild to moderate immediate allergic reactions (defined as limited in the scope of symptoms and involvement of organ systems or even localized to the site of administration) after a previous dose of authorized COVID-19 vaccines or any of its components."[5]

The J&J and AZ vaccines are an option for these folks.[4][5] PEG is found in lots of over the counter medications, skin care products, contact lens solutions, ultrasound gel,[5] and laxatives.[10]

Polysorbate 80

checkY For those with a severe polysorbate 80 allergy, J&J and Az should not be used.[5] This substance is found in cosmetics and a number of medications.[5]

Individuals with suspected but unproven allergy to a vaccine component (e.g. PEG) may be routinely vaccinated and do not need a specific assessment regarding this suspected allergy.[5]

Alcohol

Green checkmarkY "The Pfizer and Moderna vaccines do not contain alcohol. The Oxford/AstraZeneca vaccine contains ethanol (alcohol) as an excipient."[6]

Stevens-Johnson syndrome

Green checkmarkY A history of SJS is not generally a contraindication; however, if it occurred post a vaccine than discussion with an allergist is recommended.[6]

Bleeding disorders

Green checkmarkY "In individuals with bleeding disorders, the condition should be managed prior to immunization to minimize the risk of bleeding. Individuals receiving long-term anticoagulation are not considered to be at higher risk of bleeding complications following immunization and may be safely immunized without discontinuation of their anticoagulation therapy."[5]

Myocarditis

Green checkmarkY Those with a history of myocarditis or pericarditis, unrelated to the mRNA vaccine and more than six months prior, can be vaccinated with mRNA vaccines per the Australian Technical Advisory Group on Immunisation.[11] Other vaccines can be used.

Cancer

Green checkmarkY "CDC recommends that people whose immune systems are moderately to severely compromised and who received two doses of an mRNA COVID-19 vaccine (Pfizer-BioNTech or Moderna) receive a third dose of the same vaccine. According to CDC, such people include those who: Are being treated for blood cancer (leukemia, lymphoma, or multiple myeloma). Have received a stem cell transplant within the past 2 years."[12]

"If you recently received cancer treatment that suppresses the immune system—such as chemotherapy, a stem cell or bone marrow transplant, or cell therapy—your doctor may suggest that you wait until your immune system has recovered before you get vaccinated. Or your doctor may suggest that you wait a few weeks after vaccination to get immunosuppressive treatment."[12] This is so that the vaccine works better, not that it is contraindicated.

"Several oncology groups are recommending that people wait 4‒6 weeks after completing COVID-19 vaccination before getting a mammogram".[12]

Children

checkY Israel as of Jul 29th starting giving Pfizer to children 5 to 11 years old who are at high risk. High risk include "severe autoimmune diseases, chronic lung problems, heart failure, sickle cell anemia, a body mass index (BMI) over the 99th percentile, and neurodevelopmental disorders."[13]

A vaccine is expected to be approved mid winter 2021 in the United States for kids under 12.[14] Off label use is discouraged until this time.[15]

Immune storm

Green checkmarkY On Facebook concerns regarding cytokine store has been put forwards as a reason people cannot be vaccinated. There however is "no evidence to suggest mRNA vaccines will cause a cytokine storm".[16]

Capillary leak syndrome

Green checkmarkY Not a contraindication. People may receive mRNA vaccines.[17]

Cerebral venous sinus thrombosis

Green checkmarkY May receive mRNA vaccines.[17]

Doses given in BC

References

  1. ↑ Canada, Public Health Agency of (25 March 2021). "COVID-19: Pregnancy, childbirth and caring for a newborn". www.canada.ca. Retrieved 24 August 2021.
  2. ↑ 2.0 2.1 2.2 "COVID-19 Vaccination Considerations for Persons with Underlying Medica". Centers for Disease Control and Prevention. 19 August 2021. Retrieved 24 August 2021.
  3. ↑ "ACR Announcements: Coronavirus Disease (COVID-19)". www.rheumatology.org. Retrieved 24 August 2021.
  4. ↑ 4.0 4.1 4.2 "COVID-19 Vaccination". Centers for Disease Control and Prevention. 11 February 2020.
  5. ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 Canada, Public Health Agency of (14 December 2020). "Recommendations on the use of COVID-19 vaccines". www.canada.ca. Retrieved 24 August 2021.
  6. ↑ 6.0 6.1 6.2 "COVID VACCINE ALLERGY FAQs for GPs". Retrieved 24 August 2021.
  7. ↑ Krantz, Matthew S.; Kwah, Jason H.; Stone, Cosby A.; Phillips, Elizabeth J.; Ortega, Gilbert; Banerji, Aleena; Blumenthal, Kimberly G. (26 July 2021). "Safety Evaluation of the Second Dose of Messenger RNA COVID-19 Vaccines in Patients With Immediate Reactions to the First Dose". JAMA Internal Medicine. doi:10.1001/jamainternmed.2021.3779.
  8. ↑ "Advising individuals with allergies on their suitability for COVID-19 Vaccine Pfizer-BioNTech". SPS - Specialist Pharmacy Service. Retrieved 24 August 2021.
  9. ↑ "Polyethylene glycol allergy". Oak Brook Allergists. 21 December 2020. Retrieved 24 August 2021.
  10. ↑ "Polyethylene glycol (PEG) laxatives and starch-based thickeners: potential interactive effect when mixed, leading to an increased risk of aspiration". GOV.UK. Retrieved 27 December 2021.
  11. ↑ "Guidance on Myocarditis and Pericarditis after mRNA COVID-19 Vaccines" (PDF). Retrieved 24 August 2021.
  12. ↑ 12.0 12.1 12.2 "Coronavirus: What People with Cancer Should Know - National Cancer Institute". www.cancer.gov. 13 March 2020. Retrieved 24 August 2021.
  13. ↑ "Israel to give COVID vaccine to high-risk kids | Healthing.ca". 29 July 2021. Retrieved 24 August 2021.
  14. ↑ "Covid vaccines for kids under 12 expected midwinter, FDA official says". NBC News. Retrieved 24 August 2021.
  15. ↑ "FDA Discourages Off-Label Use Of COVID-19 Vaccines In Kids Under 12 | InsideHealthPolicy.com". insidehealthpolicy.com. Retrieved 24 August 2021.
  16. ↑ Staff, Reuters (21 January 2021). "Fact check: There is no evidence that mRNA vaccines would cause recipients to suffer from a 'cytokine storm'". Reuters. Retrieved 24 August 2021.
  17. ↑ 17.0 17.1 "Valid contraindications and deferrals to COVID-19 vaccination" (PDF). Retrieved 16 September 2021.
Retrieved from "https://mdwiki.org/w/index.php?title=WikiProjectMed:Vaccine&oldid=1278383"