Video:Mpox

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Description

Mpox, formerly known as monkeypox, is an infectious viral disease that can occur in both humans and some other animals.[1][2]

Symptoms2

It typically presents with one or many blisters associated with fever, muscle aches, sore throat, fatigue, or swollen glands.[1]

Symptoms2

The time from exposure to onset of symptoms is typically a few days, though may range from 1 to 21 days.[1]

Symptoms3

Over a duration of 2 to 4 weeks the bumps tend to progress from small bumps to itchy painful pus filled blisters.[1] These may have a dip in the centre.[1] They then become sores that crust and scab.[1]

Symptoms4

These sores are generally seen on the palms of hands and soles of feet,[1]

Symptoms5

the throat,[1]

Symptoms6

the genitals,[1]

Symptoms7

and the face, though may occur anywhere.[1]

Symptoms8

Other symptoms may include a headache, backache, and pain in the rectum or on passing urine.[1]

Complications

Complications include bacterial skin infection, brain, heart, or prostate inflammation, urinary tract infections, pneumonia, visual loss, and death.[1]

Cause

Mpox is caused by the monkeypox virus, which belongs to the same family as smallpox.[1] Its natural reservoir is not known.[1][2]

Infectiousness1

The virus spreads from one person to another by direct contact with affected skin or sores in the mouth or genitals.[1]

Infectiousness2

This includes face-to-face contact, touching or genital sex, kissing, oral sex, or respiratory droplets.[1]

Infectiousness3

Infected animals can pass empox to humans via bites or scratches, or during hunting, skinning, trapping, cooking, or eating animals.[1]

Infectiousness4

Contaminated clothing, sharps injuries and tattoo procedures may increase the risk.[1] It is contagious until all the sores have healed.[1]

Diagnosis

Diagnosis is by its appearance and taking a swab of the sores, mouth, rectum or anus.[1]

Differential1

The disease should be distinguished from other infectious diseases such as measles,[1]

Differential2

bacterial skin infections,[1]

Differential3

scabies,[1]

Differential4

herpes, and[1]

Differential5

syphilis,[1]

Differential6

and non-infectious conditions such as a drug reaction.[1]

Differential7

Mpox may look like chicken pox or occur with chicken pox at the same time.[1]

Prevention1

Prevention is with hygiene measures such as hand washing and staying away from affected people.[1]

Prevention2

If exposed to the virus, a vaccine is available in some parts of the world, and is recommended within 4 days of contact with someone who has mpox.[1] The antiviral tecovirimat has been used to treat mpox.[1]

Epidemiology1

It has been endemic in parts of Central and West Africa.[2]

Epidemiology2

The twenty twenty two to twenty twenty three outbreak marked the first time empox had spread widely outside Central and West Africa.[3]

Epidemiology3

Then the virus mostly spread through sexual contact.[4]

Epidemiology4

In August 2024, for the second time, the World Health Organization declared mpox a Public Health Emergency of International Concern.[4]

History

The Monkeypox virus was discovered in 1958 in colonies of monkeys kept for research.[2]

References

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 1.21 1.22 1.23 1.24 1.25 1.26 1.27 1.28 1.29 "Mpox (monkeypox)". www.who.int. World health Organization. Retrieved 14 August 2024.
  2. 2.0 2.1 2.2 2.3 "Monkeypox in the U.S." Centers for Disease Control and Prevention. CDC. 22 July 2022. Archived from the original on 15 October 2017. Retrieved 29 July 2022.
  3. Sample, Ian (2 November 2023). "Mpox circulated for five years before global explosion in 2022, research finds". The Guardian. ISSN 0261-3077. Archived from the original on 1 July 2024. Retrieved 1 December 2023.
  4. 4.0 4.1 "Mpox". www.who.int. World Health Organization. Retrieved 18 August 2024.