Vesicle (dermatology)

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Vesicles due to eczema
SymptomsVery small fluid-filled blister in skin[1]

A vesicle is a very small fluid-filled blister in skin.[1] It may have one cavity or several compartments.[1] The fluid may be clear, yellowish, or blood stained.[2] It may be dome shaped or have a central depression.[1] A vesicle may occur on its own, or there may be many, either dispersed irregularly or grouped in a line or cluster.[1] It may be present deep in skin or superficial.[3]

Vesicles may arise from small flat spots or small bumps.[4] If they merge they may form larger blisters.[4] Vesicles can burst and form into ulcers or fill with pus to become pustules.[4] Conditions that may present with vesicles include allergic reactions, shingles and herpes simplex.[4]

Signs and symptoms


  1. 1.0 1.1 1.2 1.3 1.4 James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "2. Cutaneous signs and diagnosis". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. p. 11. ISBN 978-0-323-54753-6.
  2. Bolognia, Jean L.; Schaffer, Julie V.; Duncan, Karynne O.; Ko, Christine (2022). "1. Basics". Dermatology Essentials (2nd ed.). Elsevier. p. 6. ISBN 978-0-323-70971-2. Archived from the original on 2024-02-12. Retrieved 2024-02-12.
  3. Morris-Jones, Rachael (2019). "1. Introduction". In Morris-Jones, Rachael (ed.). ABC of Dermatology (7th ed.). Hoboken: Wiley Blackwell. p. 3. ISBN 978-1-119-48899-6. Archived from the original on 2023-02-09. Retrieved 2023-02-09.
  4. 4.0 4.1 4.2 4.3 Langlais, Robert P.; Miller, Craig S.; Gehrig, Jill S. (2017). "18. Diagnostic and descriptive terminology: macule, patch, erosion, ulcer". Color Atlas of Common Oral Diseases, Enhanced Edition (5th ed.). Burlington: Jones & Bartlett Learning. p. 24. ISBN 978-1-284-24098-6. Archived from the original on 2023-02-09. Retrieved 2023-02-09.