Valnemulin

From WikiProjectMed
Jump to navigation Jump to search
Valnemulin
Valnemulin.svg
Clinical data
Trade namesEconor or Biotilina
AHFS/Drugs.comInternational Drug Names
Routes of
administration
By mouth (in-feed)
ATCvet code
Legal status
Legal status
  • Veterinary use only
Identifiers
  • (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl-
    5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-
    3a,9-propano-3aH-cyclopenta[8]annulen-8-yl-
    [(R)-2-(2-amino-3-methylbutanoylamino)-1,1-dimethtylethyl
    sulfanyl]acetate
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC31H52N2O5S
Molar mass564.83 g·mol−1
3D model (JSmol)
  • O=C(NCC(SCC(=O)O[C@@H]2C[C@@](\C=C)([C@@H](O)[C@@H]([C@]31[C@@H](C(=O)CC1)[C@@]2(C)[C@H](C)CC3)C)C)(C)C)[C@H](N)C(C)C
  • InChI=1S/C31H52N2O5S/c1-10-29(8)15-22(38-23(35)16-39-28(6,7)17-33-27(37)24(32)18(2)3)30(9)19(4)11-13-31(20(5)26(29)36)14-12-21(34)25(30)31/h10,18-20,22,24-26,36H,1,11-17,32H2,2-9H3,(H,33,37)/t19-,20+,22-,24-,25+,26+,29-,30+,31+/m1/s1 checkY
  • Key:LLYYNOVSVPBRGV-MVNKZKPCSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Valnemulin (trade name Econor or Biotilina) is a pleuromutilin antibiotic used to treat swine dysentery, ileitis, colitis and pneumonia. It is also used for the prevention of intestinal infections of swine.[1] Valnemulin has been observed to induce a rapid reduction of clinical symptoms of Mycoplasma bovis infection, and eliminate M. bovis from the lungs of calves.[2][3]

References

  1. ^ Econor: Product Profile
  2. ^ Stipkovits L, Ripley PH, Tenk M, Glávits R, Molnár T, Fodor L (June 2005). "The efficacy of valnemulin (Econor) in the control of disease caused by experimental infection of calves with Mycoplasma bovis". Research in Veterinary Science. 78 (3): 207–15. doi:10.1016/j.rvsc.2004.09.005. PMID 15766939.
  3. ^ ".:: CIMAVet ::. Detalle del medicamento".