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Chronic myelogenous leukemia | |
---|---|
Other names: Chronic myeloid leukemia, chronic granulocytic leukemia (CGL) | |
The Philadelphia chromosome as seen by fluorescent in situ hybridization (FISH). | |
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Specialty | Hematology and oncology |
Symptoms | Early: None, tiredness, left upper abdominal pain[1] Later: Headache, bone pain, fever, enlarged lymph nodes[1] |
Complications | Bleeding, priapism[1] |
Usual onset | 56 years old[1] |
Risk factors | Atomic bomb exposure[1] |
Diagnostic method | Complete blood cell count (CBC), cytogenetic testing[1] |
Differential diagnosis | Other causes of leukocytosis, chronic neutrophilic leukemia, polycythemia vera[1] |
Prognosis | Five-year survival rate 70%[2] |
Frequency | 298,000 (2015)[3] |
Deaths | 32,200 (2015)[4] |
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- ↑ Vos T, Allen C, Arora M, Barber RM, Bhutta ZA, Brown A, et al. (GBD 2015 Disease and Injury Incidence and Prevalence Collaborators) (October 2016). "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545–1602. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282.
- ↑ Wang H, Naghavi M, Allen C, Barber RM, Bhutta ZA, Carter A, et al. (GBD 2015 Mortality and Causes of Death Collaborators) (October 2016). "Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1459–1544. doi:10.1016/s0140-6736(16)31012-1. PMC 5388903. PMID 27733281.