|Eyelash trichomegaly-eyelashes became excessively elongated, curly and irregular ( erlotinib)|
Trichomegaly is a congenital condition in which the eyelashes are abnormally long, greater than 12mm in the central area and 8mm in the peripheral. The term was first used by H. Gray in 1944 in a publication in the Stanford Medical Bulletin, though he was only the third person to characterize the disorder; the first two reports were published in German in 1926 and 1931 by Reiter and Bab, respectively. Gray suggested the use of the term "movie lashes" to describe this condition, for long lashes were at the time being portrayed in film as a desirable characteristic in women.
There are several causal agents for this disorder; these can be divided into three main categories and include the following:
- Oliver–McFarlane syndrome
- Cornelia de Lange Syndrome
- Cone-rod dystrophy
- Tetralogy of Fallot
- Hermansky–Pudlak syndrome
- Goldstein Hutt Syndrome
- Phylloid hypomelanosis
- Smith-Lemli-Opitz Syndrome
- Areata alopecia
- Connective tissue disorders, such as
- Renal metastatic Adenocarcinoma
- Eating disorders, such as Anorexia nervosa
- Prostaglandin analogues
- Bimatoprost, Latanoprost
- Systemic corticosteroids
Diagnosis , genetic not acquired, can be done via genetic tests
- Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 1010. ISBN 978-1-4160-2999-1.
- Paul, Laura J.; Cohen, Philip R.; Kurzrock, Razelle (2012-06-01). "Eyelash trichomegaly: review of congenital, acquired, and drug-associated etiologies for elongation of the eyelashes". International Journal of Dermatology. 51 (6): 631–646. doi:10.1111/j.1365-4632.2011.05315.x. ISSN 1365-4632. PMID 22607279.
- Ziakas, N. G.; Jogiya, A.; Michaelides, M. (2004-01-30). "A case of familial trichomegaly in association with oculocutaneous albinism type 1". Eye. 18 (8): 863–864. doi:10.1038/sj.eye.6701326. ISSN 0950-222X. PMID 14752500.
- Fernández-Crehuet, Pablo; Ruiz-Villaverde, Ricardo (2016). "Essential Trichomegaly of the Eyelashes". International Journal of Trichology. 8 (3): 153–154. doi:10.4103/0974-7753.189031. ISSN 0974-7753. PMC 5007925. PMID 27625571.
- "Clinical and research tests for C0854699 - Genetic Testing Registry (GTR) - NCBI". www.ncbi.nlm.nih.gov. Archived from the original on 25 April 2022. Retrieved 24 April 2022.