Trichomegaly
| Trichomegaly | |
|---|---|
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| Eyelash trichomegaly-eyelashes became excessively elongated, curly and irregular ( erlotinib) | |
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| Specialty | Dermatology |
Trichomegaly is a congenital condition in which the eyelashes are abnormally long,[1] greater than 12mm in the central area and 8mm in the peripheral. The term was first used by H. Gray in 1944 in a publication in the Stanford Medical Bulletin,[2] though he was only the third person to characterize the disorder; the first two reports were published in German in 1926 and 1931 by Reiter and Bab, respectively.[3] Gray suggested the use of the term "movie lashes" to describe this condition, for long lashes were at the time being portrayed in film as a desirable characteristic in women.
Causes
There are several causal agents for this disorder; these can be divided into three main categories and include the following:[4]
Congenital Syndromes
- Oliver–McFarlane syndrome
- Cornelia de Lange Syndrome
- Cone-rod dystrophy
- Tetralogy of Fallot
- Hermansky–Pudlak syndrome
- Goldstein Hutt Syndrome
- Phylloid hypomelanosis
- Smith-Lemli-Opitz Syndrome
Acquired disorders
- Areata alopecia
- Connective tissue disorders, such as
- Lupus
- Dermatomyositis
- Hen fever
- Atopic dermatitis
- HIV/AIDS
- Renal metastatic Adenocarcinoma
- Eating disorders, such as Anorexia nervosa
- Pregnancy
Drugs
- Prostaglandin analogues
- Cetuximab
- Bimatoprost, Latanoprost
- Phenytoin
- Minoxidil
- Ciclosporin
- Topiramate
- Streptomycin
- Systemic corticosteroids
- Penicillamine
Diagnosis
Diagnosis , genetic not acquired, can be done via genetic tests[5]
See also
References
- ↑ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 1010. ISBN 978-1-4160-2999-1.
- ↑ Paul, Laura J.; Cohen, Philip R.; Kurzrock, Razelle (2012-06-01). "Eyelash trichomegaly: review of congenital, acquired, and drug-associated etiologies for elongation of the eyelashes". International Journal of Dermatology. 51 (6): 631–646. doi:10.1111/j.1365-4632.2011.05315.x. ISSN 1365-4632. PMID 22607279.
- ↑ Ziakas, N. G.; Jogiya, A.; Michaelides, M. (2004-01-30). "A case of familial trichomegaly in association with oculocutaneous albinism type 1". Eye. 18 (8): 863–864. doi:10.1038/sj.eye.6701326. ISSN 0950-222X. PMID 14752500.
- ↑ Fernández-Crehuet, Pablo; Ruiz-Villaverde, Ricardo (2016). "Essential Trichomegaly of the Eyelashes". International Journal of Trichology. 8 (3): 153–154. doi:10.4103/0974-7753.189031. ISSN 0974-7753. PMC 5007925. PMID 27625571.
- ↑ "Clinical and research tests for C0854699 - Genetic Testing Registry (GTR) - NCBI". www.ncbi.nlm.nih.gov. Archived from the original on 25 April 2022. Retrieved 24 April 2022.
