Thyrotropin alfa

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Thyrotropin alfa
Clinical data
Drug classThyroid stimulating hormone[1]
Main usesThyroid cancer[1]
Side effectsNausea, headache[1]
External links

Thyrotropin alfa, sold under the brand name Thyrogen is a medicine used to find remaining thyroid tissue after surgery.[2] Specifically it is used in thyroid cancer in addition to thyroglobulin testing.[1] It is given by injection into a muscle.[1]

Common side effects include nausea and headache.[1] Other side effects may include high thyroid in those who still have functional thyroid tissue, stroke, and increased thyroid tumor size.[1] It is a manufactured form of thyroid stimulating hormone.[1]

Thyrotropin alfa was approved for medical use in the United States in 1998 and Europe in 2000.[1][3] In the United States it costs about 3,700 USD for a course of treatment.[4] In the United Kingdom this amount costs the NHS about £580.[2]

Medical uses


It is given as two doses of 0.9 mg separated by a day.[1] The last dose may be followed by radioactive iodine or nuclear medicine scanning.[1]


  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 "Thyrotropin Alfa Monograph for Professionals". Archived from the original on 4 March 2021. Retrieved 4 October 2021.
  2. 2.0 2.1 BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 813. ISBN 978-0-85711-369-6.{{cite book}}: CS1 maint: date format (link)
  3. "Thyrogen". Archived from the original on 10 April 2021. Retrieved 5 October 2021.
  4. "Thyrogen Prices, Coupons & Patient Assistance Programs". Archived from the original on 27 January 2021. Retrieved 5 October 2021.