Template
:
Lipid signaling
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v
t
e
Cell signaling
:
lipid signaling
Extracellular
Eicosanoids
Classic:
Eoxins
;
Leukotrienes
(
LTR
)
Prostacyclin
(
IPR
)
Prostaglandins
(
PGR
)
Thromboxane
(
TXR
)
Nonclassic:
EETs
Endocannabinoids
(
CBR
)
Epi-lipoxins
(
FPR2
)
Hepoxilins
Isoprostanes
Lipoxins
(
FPR2
)
Oxoeicosanoids
(
OXER
)
Resolvins
(
FPR2
)
Lysophospholipids
LPA
(
LPAR
)
S1P
(
S1PR
)
Steroids
Bile acids
(
GPBAR
)
Neurosteroids
Pheromones
(
VNR
)
Others
PAF
(
PAFR
)
Retinal
(
RHO
)
Intracellular
Nuclear receptor
Steroids:
Sex steroids:
Androgens
(
AR
)
Estrogens
(
ER
)
Progestogens
(
PR
);
Corticosteroids:
Glucocorticoids
(
GR
)
Mineralocorticoids
(
MR
);
Others:
Bile acids
(
FXR
)
Calcitriol
(
VDR
);
Others:
Eicosanoids
(
PPAR
)
Free fatty acids
(
PPAR
)
Retinoic acid
(
RAR
,
RXR
)
Second messenger
General:
Arachidonic acid
DAG
(
PKC
,
TRPC
)
IP
3
(
IP
3
R
,
RyR
)
Phosphatidic acid
Phosphoinositides:
PIP
2
(
IRKs
)
PIP
3
(
PKB/Akt
,
Btk
,
PDPK1
)
PtdIns(3,4)P
2
(
PKB/Akt
,
PDPK1
);
Sphingolipids:
C1P
Ceramide
(
CAPPs
,
KSR1
,
PKCζ
,
CTSD
)
Glucosylceramides
S1P
Sphingosine
(
SDK1
,
PKH
,
YPK
)
Precursors
General
Fatty acids
(
ω-3
,
ω-6
)
Steroids
Squalene
Lanosterol
Cholesterol
Category
:
Signaling pathway templates
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