Telmisartan/amlodipine
Combination of | |
---|---|
Telmisartan | Angiotensin II receptor antagonist |
Amlodipine | Calcium channel blocker |
Names | |
Trade names | Twynsta, others |
Clinical data | |
Routes of use | By mouth |
Defined daily dose | not established[1] |
Legal | |
Legal status |
|
Telmisartan/amlodipine, sold under the brand name Twynsta among others, is a medication used to treat high blood pressure.[2] It is a combination of telmisartan an angiotensin II receptor antagonist with amlodipine a calcium channel blocker.[2] It is taken by mouth.[2]
Common side effects include dizziness, swelling, and back pain.[2] Severe side effects may include low blood pressure, kidney problems, electrolyte problems, and a heart attack.[2] Use during pregnancy may harm the baby.[2] Telmisartan works by blocking the effects of angiotensin II while amlodipine works by decreasing calcium ion entry into smooth muscle and heart muscle.[2]
The combination was approved for medical use in the United States in 2009.[2] The combination is on the World Health Organization's List of Essential Medicines.[3] It is available as a generic medication.[4] In the United States it costs at least US$57 per month as of 2019.[5]
Dosage
The defined daily dose is not established.[1]
References
- ↑ 1.0 1.1 "WHOCC - ATC/DDD Index". www.whocc.no. Archived from the original on 1 July 2021. Retrieved 10 September 2020.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 "DailyMed - TELMISARTAN AND AMLODIPINE tablet". dailymed.nlm.nih.gov. Archived from the original on 28 February 2020. Retrieved 30 October 2019.
- ↑ "World Health Organization model list of essential medicines: 21st list 2019". 2019. hdl:10665/325771.
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(help) - ↑ "Telmisartan and Amlodipine (Professional Patient Advice)". Drugs.com. Archived from the original on 30 October 2019. Retrieved 30 October 2019.
- ↑ "Amlodipine/telmisartan Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 30 October 2019. Retrieved 30 October 2019.
External links
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