|Telmisartan||Angiotensin II receptor antagonist|
|Amlodipine||Calcium channel blocker|
|Trade names||Twynsta, others|
|Defined daily dose||not established|
Telmisartan/amlodipine, sold under the brand name Twynsta among others, is a medication used to treat high blood pressure. It is a combination of telmisartan an angiotensin II receptor antagonist with amlodipine a calcium channel blocker. It is taken by mouth.
Common side effects include dizziness, swelling, and back pain. Severe side effects may include low blood pressure, kidney problems, electrolyte problems, and a heart attack. Use during pregnancy may harm the baby. Telmisartan works by blocking the effects of angiotensin II while amlodipine works by decreasing calcium ion entry into smooth muscle and heart muscle.
The combination was approved for medical use in the United States in 2009. The combination is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. It is available as a generic medication. In the United States it costs at least US$57 per month as of 2019.
- "WHOCC - ATC/DDD Index". www.whocc.no. Retrieved 10 September 2020.
- "DailyMed - TELMISARTAN AND AMLODIPINE tablet". dailymed.nlm.nih.gov. Retrieved 30 October 2019.
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- "Telmisartan and Amlodipine (Professional Patient Advice)". Drugs.com. Retrieved 30 October 2019.
- "Amlodipine/telmisartan Prices, Coupons & Patient Assistance Programs". Drugs.com. Retrieved 30 October 2019.