Talk:Trofosfamide
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Amide vs. amine
There are (at least) three Wikipedia articles about related substances:
ifosfamide
trofosfamide
cyclophosphamide
The systematic names given in the articles are as follows:
ifosfamide = N-3-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-AMIDE-2-oxide
trofosfamide = N,N,3-tris(2-chloroethyl)-1,3,2-oxazaphosphinan-2-AMIDE 2-oxide
cyclophosphamide = N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-AMINE 2-oxide
(capitalization added for emphasis). The question here is why ifosfamide and trofosfamide are considered "amides" while cyclophosphamide is considered an "amine". None of these substances has the characteristic CONH2 group. Either they are all amines or they are all amides. Which one is correct? Thomas.Hedden (talk) 00:24, 21 June 2011 (UTC)