Talk:Tioguanine

From WikiProjectMed
Jump to navigation Jump to search

Very inaccurate

I think this piece is a scandal. Someone who is not very informed about 6-TG has written this. The article about 6-mercaptopurine (which is intracellularly converted to 6-TG) is much better.

I dont have time to correct all this, sorry. I work in a cancer research lab, where I analyze the amount of deoxy-6-Thioguanine in patient DNA (yes, the patients get 6MP - not 6TG) —Preceding unsigned comment added by 130.226.107.2 (talk) 13:34, 28 October 2009 (UTC)[reply]

Agreed...I was thinking about translating this into Chinese, but found its quality is too poor. The same goes for Melphalan, Dacarbazine, Procarbazine, Cyclosporin. The German versions are much better.--Jsjsjs1111 (talk) 12:40, 21 June 2012 (UTC)[reply]

Major edit

I am undertaking a major revision of this article - the above criticisms are very true. As the German version is far better, I am basing my revision on this, but with updates. This drug is undergoing a resurgence of interest - latest references will be included. Introductory part finished so far (24 Aug, 1715 Aust EST), more to follow. I have published widely on the topic of thiopurines and more specifically thioguanine in recent times, and am happy to supply details if required. — Preceding unsigned comment added by Johnaduley (talkcontribs) 07:15, 24 August 2012 (UTC)[reply]

Revision completed 26 Aug. — Preceding unsigned comment added by Johnaduley (talkcontribs) 10:54, 26 August 2012 (UTC)[reply]

Why was the name changed?

Does anyone know the reasoning behind the INN name change? Current literature still seems to be using Thioguanine, while Tioguanine seems to be widely used by manufacturers. I'm baffled why it would need to change from Thioguanine. Is it possible to find a reference for the INN change? — Preceding unsigned comment added by 67.171.167.38 (talk) 23:12, 24 May 2013 (UTC)[reply]