Talk:Telmisartan

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Telmisartan is an ARB, should be mentioned at the lede

Being an ARB is a vital info for Telmisartan, dont you fellow wikipedians think it should be mentioned somehow at the lede? Pinging Doc James.Cheers. Cinadon36 19:04, 25 November 2019 (UTC)[reply]

User:Cinadon36 It is mentioned in the lead with " It is a angiotensin II receptor antagonist and works by blocking the effects of angiotensin II."
I have also added it to the infobox. Doc James (talk · contribs · email) 19:10, 25 November 2019 (UTC)[reply]
Yes I had noticed, it is just that the specific sentence mentions the mechanism of action of Telmisartan, a reader that is unfamiliar with the specific pathway won't think that there is a group of drugs- the sartans- and Telmisartan is one of them. Cinadon36 19:13, 25 November 2019 (UTC)[reply]
I now saw you 've added it at the infobox. Much better now. Thanks. Cinadon36 19:15, 25 November 2019 (UTC)[reply]

"Telmisartan, sold under the trade name Micardis among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease"

I do not like this sentence. Telmisartan is mostly an anti-HTN drug, its use/role at heart failure or CKD is not as notable as its role at HTN. Also, and more importantly, it is not used as a treatment of HF or CKD, it is used in the management of those to diseases. I would have change the sentence to "Telmisartan, sold under the trade name Micardis among others, is a medication used to treat high blood pressure. It is also used in the management of heart failure and diabetic kidney disease" but since it is the first sentence, I need your opinion...Cinadon36 20:16, 25 November 2019 (UTC)[reply]

PPARg-agonist activity of Telmisartan

Telmisartan has a PPARg-agonist- activity It says so at Opie, 8th edition, 2013, p171. I am not sure if we should state it at the article as it is mentioned in a secondary sentence... I feel the PPARg-agonist activity is really low. Same page says that telmisartan "reduced new-onset electrocardiographic LVH by 37%".Cinadon36 09:37, 26 November 2019 (UTC)[reply]