Talk:Rabies vaccine

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Wiki Education Foundation-supported course assignment

This article was the subject of a Wiki Education Foundation-supported course assignment, between 4 September 2019 and 4 December 2019. Further details are available on the course page. Student editor(s): Jmg613.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 07:40, 17 January 2022 (UTC)[reply]

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One of the more interesting things about the rabies vaccine ioooiis the fact that, unlike most vaccines, it can be administered after exposure. That is; you can go to the doctor and get the vaccine after you've been bitten. This is because rabies has an unusually long incubation time (10 days to 10 years, but usually 2-8 weeks), allowing the body to build up defences if given the vaccine in time. (within 3 days is recommended)

For post-exposition prophylaxis you need five doses instead of three. As far as I know, not all patients respond to post-expo prophylaxis, whereas I know of no reported cases of a patient dying from rabies when they were immunised preemptively. --ἀνυπόδητος (talk) 08:08, 1 August 2010 (UTC)[reply]

The vaccine itself is not one, but a series of three shots (given on days 0, 7 and 28). It's given in the deltoid muscle. (the shoulder)

The vaccine can be given in advance, to provide immunity, but since it can be given after exposure, it is usually only given to people who are at very high risk of exposure, or if travelling somewhere isolated and high risk, where the vaccine will not be available.

Sorry I cbf logging in to my wikipedia account, I don't do this often enough and forgot my password. You'll just have to deal with my IP address =P

sources here: http://www.vaccineinformation.org/rabies/qandavax.asp http://www.nevdgp.org.au/info/travel/dis/rabies.htm

someone who's a wiki regular please add this info to the page.

thanks in advance! <3 60.240.32.184 (talk) 22:36, 30 May 2010 (UTC)[reply]

Possible Interesting Addition In its original form I believe this vaccine was injected directly into the spine (through the front of the abdomen). I came here to see if this was (still) the case. Mattbondy (talk) 18:14, 24 June 2010 (UTC)[reply]

Are you serious? With a ten inch needle? --ἀνυπόδητος (talk) 08:08, 1 August 2010 (UTC)[reply]


COST OF RABIES VACCINE.

COST OF RABIES SHOTS. A buddy told me on April 26, 2013, that he recently had to get rabies shots. He was irked his insurance did not cover the cost of the rabies vaccine. He said the cost was "$2,000.00." Also, he had to drive about 40 miles from his home town of 15,000 people to get the vaccine and bring it back. Is that a good approximate cost?

Robert in Austin, Texas.


Length of Protection: I noticed that the article lacks this information; I found it, in various sources (some commercial, though) to be 2 to 3 years; please someone with wiki editing skills add this informations!
sources:
http://www.spmsd.co.uk/file.asp?docid=140, page 3
http://www.travelturtle.co.uk/Vaccine_Details.aspx?confoundingFactorId=61
http://www.phac-aspc.gc.ca/publicat/ccdr-rmtc/02vol28/28sup/acs4.html
Dr Black Knife (talk) 18:15, 31 August 2010 (UTC)[reply]

Nevermind, I did it. Expansion of this section, though, would be most useful!
Dr Black Knife (talk) 18:58, 31 August 2010 (UTC)[reply]

Proposed merge with Oral vaccination against rabies

Oral vaccination against rabies is an unnecessary content fork. There are already several distinct articles on rabies, which makes it harder to quickly gain information. Oral vaccines are a type of vaccine, so there is no reason to keep them separate. --Animalparty-- (talk) 23:45, 20 February 2014 (UTC)[reply]

DOne Doc James (talk · contribs · email) (if I write on your page reply on mine) 00:22, 21 February 2014 (UTC)[reply]

Cost

Do we have any referenced data on cost of the vaccine? RJFJR (talk) 17:19, 27 June 2014 (UTC)[reply]

Verorab

This is the brand name of the vaccine given a friend after a recent dog bite. I can't seem to find any hard data on this name brand. Is there a Doctor in the house?Ernest Ruger (talk) 17:47, 16 September 2014 (UTC)[reply]

See WHO page. Ruslik_Zero 19:14, 16 September 2014 (UTC)[reply]

The WHO page link is now dead.

--91.159.191.233 (talk) 18:56, 19 January 2022 (UTC)[reply]

COI editing

Editors from a company selling a rabies vaccine are editing this article, with declaring their connection to the company - see tag at top of this page. I tagged the article itself. per the message on that tag, it needs to stay until an independent editor reviews the article to ensure it complies with WP:NPOV. Jytdog (talk) 19:59, 26 February 2015 (UTC)[reply]

suggestion

First sentence: In a full sentence, should not "vaccine" always have an article? Thus, the first sentence should start with "The rabies vaccine" instead of "Rabies vaccine". Piojo (talk) 08:04, 6 March 2015 (UTC)[reply]

done, thanks, Jytdog (talk) 14:13, 6 March 2015 (UTC)[reply]

External links modified

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Recombinant rabies vaccine

The content below needs independent, secondary sourcing; the claim that the vaccine described in the paper is the one sold by Merial is entirely unsourced.

Aerially distributed wildlife rabies vaccine in a bait from Estonia.

In 1984 researchers at the Wistar Institute developed a recombinant vaccine called V-RG by inserting the glycoprotein gene from rabies into a vaccinia virus.[1] It is harmless to humans and has been shown to be safe for various species of animals that might accidentally encounter it in the wild, including birds (gulls, hawks, and owls).[2]

V-RG has been successfully used to prevent outbreaks of rabies in wildlife. The vaccine is stable under relatively high temperatures and can be delivered orally, making mass vaccination of wildlife possible by putting it in baits. The plan for immunization of normal populations involves dropping bait containing food wrapped around a small dose of the live virus. The bait would be dropped by helicopter concentrating on areas that have not been infected yet. In November 2008, Germany had been free of new cases for two years and is therefore currently believed to be rabies-free, together with a few other countries. A strategy of vaccinating “neighborhood dogs” in Jaipur, India, combined with a sterilization program, has also resulted in a large reduction in the number of human cases.[3]

References

  1. ^ Wiktor TJ, Macfarlan RI, Reagan KJ, Dietzschold B, Curtis PJ, Wunner WH, Kieny MP, Lathe R, Lecocq JP, Mackett M; MacFarlan; Reagan; Dietzschold; Curtis; Wunner; Kieny; Lathe; Lecocq; MacKett (1984). "Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene". Proc. Natl. Acad. Sci. U.S.A. 81 (22): 7194–8. doi:10.1073/pnas.81.22.7194. PMC 392104. PMID 6095272.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. ^ Artois M, Charlton KM, Tolson ND, Casey GA, Knowles MK, Campbell JB; Charlton; Tolson; Casey; Knowles; Campbell (1990). "Vaccinia recombinant virus expressing the rabies virus glycoprotein: safety and efficacy trials in Canadian wildlife". Can. J. Vet. Res. 54 (4): 504–7. PMC 1255701. PMID 2249183.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. ^ Reece JF, Chawla SK.; Chawla (2006). "Control of rabies in Jaipur, India, by the sterilisation and vaccination of neighbourhood dogs". Vet Rec. 159 (12): 379–83. doi:10.1136/vr.159.12.379. PMID 16980523.

-- Jytdog (talk) 15:10, 21 October 2016 (UTC)[reply]

Organizing the "Other animals" section

The animals section is a mess. May I suggest 2 possible ways of organizing it into coherent subsections and can people say which they think will be better?

  • By type of animal: Vaccines for domestic animals / Vaccines for wildlife
  • By type of vaccine: Modified live / Inactivated / Recombinant viral vector

Xenobiologista (talk) 13:19, 3 May 2017 (UTC)[reply]

By animal type seems to work. Doc James (talk · contribs · email) 19:40, 3 May 2017 (UTC)[reply]

Link for citation needed under history

I have a source for [citation needed] under history, but Wikipedia's edit function does my head in, and I invariably mess it up So here's the source for those who can navigate the Wikipedia edit function

https://academic.oup.com/cid/article-abstract/2/3/433/500366

and the bibtex

@article{doi:10.1093/clinids/2.3.433,

author = {Plotkin, Stanley A.},

title = {Rabies Vaccine Prepared in Human Cell Cultures: Progress and Perspectives},

journal = {Reviews of Infectious Diseases},

volume = {2},

number = {3},

pages = {433-448},

year = {1980},

doi = {10.1093/clinids/2.3.433},

URL = { + http://dx.doi.org/10.1093/clinids/2.3.433},

eprint = {/oup/backfile/content_public/journal/cid/2/3/10.1093/clinids/2.3.433/2/2-3-433.pdf} }

I added it. Ruslik_Zero 20:55, 3 September 2017 (UTC)[reply]

multiple infobox

@DocJames: I added the additional infoboxes because the template doesn't support more than two entries for some parameters including DrugBank and UNII -- DB10283/C6547J35OD, DB10062/C4HQF74XMW and DB11603/95F619ATQ2. See discussion at Talk:Dengue vaccine and Template_talk:Infobox_drug#Multiple_entries_for_various_parameters Whywhenwhohow (talk) 01:08, 29 December 2019 (UTC)[reply]

The DrugBank mappings may be wrong. The UNII for Immovax is C4HQF74XMW and the UNII for Rabavert is FK894Q51YE. Whywhenwhohow (talk) 05:36, 29 December 2019 (UTC)[reply]

Thimerosal

  • Why is the absence of it discussed in the lead? I don't think it is important enough for that.
  • Why is the absence of it discussed in the safety section? It's not related to the safety. It's only related to the perceived safety (and even that link is pretty weak and unsourced).

I suggest removing both. --mfb (talk) 04:33, 3 March 2021 (UTC)[reply]

No objection, so I removed them. --mfb (talk) 15:15, 13 March 2021 (UTC)[reply]

Attenuated Pasteur-Roux rabies vaccine by allowing the virus dry for 5 to 10 days

https://en.wikipedia.org/wiki/Rabies_vaccine#History

"The Pasteur-Roux vaccine attenuated the harvested virus samples by allowing them to dry for five to ten days".

Has this type of vaccine been recently used for other diseases?

Could it be this simple to develop a living covid-19 vaccine? You take a nasal sample from a covid-19 patient with a stick, and then insert the stick to your nose a few days later?

--91.159.191.233 (talk) 18:58, 19 January 2022 (UTC)[reply]

Why we should take anti rabies injection

Ins 106.200.174.159 (talk) 10:05, 4 June 2022 (UTC)[reply]

Why we should take anti rabies injection

Hindi 106.200.174.159 (talk) 10:06, 4 June 2022 (UTC)[reply]

Image

@MartinezMD: The image is decorative, it promotes a specific brand, and it is not significant. It doesn't aid in the understanding of the article. --Whywhenwhohow (talk) 07:41, 10 January 2023 (UTC)[reply]

I don't think it specifically promotes a brand. We can easily choose another or blur the brand name if you think it'll bias the reader. It does demonstrate the manner in which the vaccine is supplied, and it also gives a visual estimate of the volume involved as it looks like a fairly small amount. MartinezMD (talk) 08:52, 10 January 2023 (UTC)[reply]

Wiki Education assignment: Disease Ecology 6200

This article was the subject of a Wiki Education Foundation-supported course assignment, between 17 August 2023 and 8 December 2023. Further details are available on the course page. Student editor(s): Ryl3rs0n (article contribs). Peer reviewers: Scitalk12, Krg0302.

— Assignment last updated by Krg0302 (talk) 21:39, 27 November 2023 (UTC)[reply]

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