Talk:Mivacurium chloride
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(MIVACRON Injection)
IMPORTANT NOTE
This drug should be administered only by adequately trained individuals familiar with its actions, characteristics, and hazards.
DESCRIPTION
Mivacurium chloride (MIVACRON)is a short-acting, nondepolarizing skeletal muscle relaxant for intravenous (IV) administration.
CLINICAL PHARMACOLOGY
Mivacurium chloride binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission. This action is antagonized by acetylcholinesterase inhibitors, such as neostigmine. Mivacurium is a short-acting, nondepolarizing skeletal neuromuscular blocking agent which is hydrolyzed by plasma cholinesterase. Mivacurium results in a blockade of neuromuscular transmission by binding competitively with cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine.
INDICATIONS
Mivacurium chloride is a short-acting neuromuscular blocking agent indicated for inpatients and outpatients, as an adjunct to general anesthesia, to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.