Talk:Diethyltryptamine

Help?

Can someone convert my external links into references? Thanks in advance. --Astavats (talk) 05:34, 3 January 2008 (UTC)

Reassessment

I am reassessing this article to Start-class per request on Wikipedia:WikiProject Pharmacology/Assessment.

This article still needs a bit of work, especially in the way of expansion, before it can be assessed as B-class. It can, however, get some improvements right now that will make it a great Start-class article and help build the groundwork for B-class and GA:

1. Expand a bit on the lead. Many people will not know DMT is orally inactive and why; jumping straight into "active orally [...] without the aid of MAO inhibitors" may alienate the general audience a bit;
2. Please add a non-breaking space between numbers and units of measurement (WP:MOSNUM), and remember to italicize scientific names (MoS:T).
3. The references should, ideally, be moved into footnotes. Diberri's excellent citation builder can help you with formatting. If you don't want footnotes, you could also use the author-date system, but full references listed at the end of the article are a must!
4. Please capitalize none but the first word in a heading title, unless there are proper nouns in it.

Overall, this article can no longer be considered a stub, but there's still a bit of a way to go before it can reach B-class and GA. Best, Fvasconcellos (t·c) 10:55, 3 January 2008 (UTC)

Thanks for the break down, I'll get to fixing/adding as soon as I get time.--Astavats (talk) 12:57, 3 January 2008 (UTC)

Orally active

[1] claims it is orally active, whereas http://books.google.co.uk/books?id=WuA4LsWXXWEC says not eg deep google, also [2]

It's worth noting that Dipropyltryptamine is marked as orally inactive. Imgaril (talk) 00:11, 7 October 2011 (UTC)

I think that this book [3] notes there is a contradiction in the literature - but I don't have full access to it.Imgaril (talk) 00:17, 7 October 2011 (UTC)

Mdx92129 (talk) 16:05, 29 January 2022 (UTC)== Pharmacology ==

There is some chaff about the metabolism and administration routes of DMT, which isn't needed in an article about DET. Further, there is no reference to literature when discussing the influence of the dietyhl substituent on its oxidation by MAO.

Proposal: (1) Insert discussion of 6-hydroxylation in DET metabolism - 6-HO-DET has been detected as a minor human metabolite of DET, too. There is plenty of literature on this. Further, 6-F-DET is orally inactive, whilst DET appears to be the converse. (I can justify this by a self-experimentation, where 82mg of DET freebase (as confirmed by GC/MS analysis) per os provided an ecstatic, almost religious, experience.

(2) Remove hogwash about DMT metabolism.

I do not think self-proclaimed psychonauts should be writing sections on tryptamine pharmacology.

Mdx92129 (talk) 16:05, 29 January 2022 (UTC)