Talk:Dexlansoprazole

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Stereochemistry

Could someone check the stereochemistry of my image? It corresponds to the IUPAC name and the old PNG (which was removed due to copyright issues), but I didn't find any good sources, and this shows the S form. Thanks --ἀνυπόδητος (talk) 15:17, 9 March 2009 (UTC)[reply]

Side effects

I have heard that using Dexlansoprazole (INN, trade names Kapidex, Dexilant) a proton pump inhibitor, can permanently put the gastric juices on hold which can result in three major problems:

Inability to break down food - especially protein. Inability to kill unfriendly bacteria entering your stomach. Inability to absorb calcium.

This can easily lead to life-threatening malnourishment, embarrassing indigestion and crippling osteoporosis.

I would like to know if this is true and if so, what can I do to prevent these unwanted side effects?

— Preceding unsigned comment added by SpiritedWomanSF (talkcontribs) 09:42, 11 January 2011 (UTC)[reply]

The information is (more or less) at Proton-pump inhibitor#Adverse effects. In a nutshell, I'd say that short-term use isn't a problem. Long-term use may increase the risk of breaking a bone, especially in elderly people who have frail bones anyway. It can also increase the likeliness of infections. I wouldn't go as far as talking about "life-threatening malnourishment"; people don't die because they digest proteins more slowly.
What to do?
  • Don't take proton pump inhibitors (PPIs) longer than a few weeks without talking to your doctor. There might be a better therapy for your problem (see for example Helicobacter pylori eradication protocols).
  • Take calcium and vitamin D for your bones.
  • Live a healthy life :-) Eating healthy things like vegetables and doing some sports (in moderation) has far more positive effects on your immune system than PPIs have negative effects on your gastric acid's ability to kill germs.
  • Simethicone and enzymes help against indigestion.
Hope this helps, ἀνυπόδητος (talk) 10:17, 11 January 2011 (UTC)[reply]