Talk:Clofazimine

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Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Clofazimine.

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Other potential sources include: Centre for Reviews and Dissemination and CDC

Clofazimine

I have mentioned that Clofazimine is used in combination with rifampicin and dapsone as part of MDT for leprosy, as it is never used as monotherapy.--WHO Leprosy 15:46, 24 March 2007 (UTC)[reply]

Stereochemistry

The structure image shows the imine with a specific stereochemistry, but I think it should be drawn undefined. Neither the FDA label^[1] nor the INN^[2]^[3] give any stereochemistry for the name 'clofazimine'.

Chemically, it looks like it will be quite a labile imine, so the isomers probably interconvert with the equilibrium towards the structure currently shown (away from the steric bulk of the chlorophenylamino group) TheMikrobe (talk) 12:18, 26 January 2015 (UTC)[reply]

References

[1] "FDA".

[2] "INN recommended" (PDF).

[3] "INN proposed" (PDF).

[1]

[2]

[3]

Talk:Clofazimine

Clofazimine

Stereochemistry

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