Talk:Basement membrane

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Basement membrane is different from basal lamina and should not redirect there

Type IV versus Type III

Hello , I am confused here ...please clarify , thanks >> ..network of reticular collagen (type IV) fibrils (fibroblast precursors) which average 30 nanometers in diameter and 0.1–2 micrometers in thickness. This type III collagen is of the reticular type, .. Georges GOOSSENS 10:19, 22 November 2010 (UTC) —Preceding unsigned comment added by Georgesgoossens (talkcontribs)

Cells?

"A sheet of cells and fibers"? In Russian sources it is called an "acellular layer", ie without cells. --CopperKettle 06:43, 21 June 2009 (UTC)[reply]

Mesothelium and endothelium ARE epithelia

The present article mention "The basement membrane is a thin, fibrous, extracellular matrix of tissue that separates the epithelium (skin, respiratory tract, gastrointestinal tract, etc.), mesothelium (pleural cavity, peritoneal cavity, pericardial cavity, etc.) and endothelium (blood vessels, lymph vessels, etc.) from underlying connective tissue.[1]".

Mesothelium and endothelium ARE epithelium : therefore there's no need to add these in the sentence, since the term epithelium includes them. This could lead to confusion, and there really is no need for that. — Preceding unsigned comment added by Boson2Higgs (talkcontribs) 16:20, 7 June 2017 (UTC)[reply]

I may be confused, and you may be right, but I disagree that the three need not be mentioned. Mentioning all three (epithelium, mesothelium, and endothelium) gives the useful opportunity to describe all the types of tissue which have a basement membrane. I think that the underlying reason for confusion needs to be addressed first, namely that they all sound like three different tissue types, because they all end in -ium, even the cell type, epithelium. UnderEducatedGeezer (talk) 00:45, 11 September 2020 (UTC)[reply]

Connective tissue connection confusion?

I think there are currently some confusing statements involving 'connective tissue' between the Lead and the Structure sections, with regard to what it is that connects to the basal lamina.

I don't think the underlying connective tissue (as mentioned in the Lead) can connect to the basal lamina (as suggested in the Structure section), because the reticular lamina lies between the two.

In the Structure section, the second sentence says, "The underlying connective tissue attaches to the basal lamina with collagen VII anchoring fibrils and fibrillin microfibrils.[5]", and the first sentence says, "...the basement membrane is composed of two layers, the basal lamina and the reticular lamina.[4]". But the last sentence of the preceding Lead says, "The basement membrane sits between epithelial tissues including mesothelium and endothelium, and the underlying connective tissue.[3][4]" So I think this last sentence of the Lead defines underlying connective tissue as what's beneath the basement membrane (which is made up of the basal lamina and the reticular lamina), so it can't be what connects to the basal lamina as the second sentence of the Structure section seems to say.
I'm thinking that the Structure section may mean to say that the reticular lamina (not the underlying connective tissue) attaches to the basal lamina, because the reticular lamina is right next to the basal lamina, and the 'underlying connective tissue' is what's beneath the whole basement membrane. UnderEducatedGeezer (talk) 04:05, 3 October 2020 (UTC)[reply]

Erroneous image of basement membrane

The actual image of the basement membrane is erroreous in the way it shows it as a cellular(?) layer. Or what do the circles and stripes represent in the membrane? This should be changed immediately. — Preceding unsigned comment added by Pagurus82 (talkcontribs) 09:17, 13 October 2020 (UTC)[reply]

typo?

In the section on structure the article says 'reticular collagen IV fibrils which average 30 nanometers in diameter and 0.1–2 micrometers in thickness' Should that be '0.1 to 2 micrometers in LENGTH'? Thickness and diameter seem to be the same dimension. It would also be less confusing if the same units were used for length and width, ie, 30 nm in diameter and anywhere from 100 nm to 2,000 nm in length...' DlronW (talk) 00:28, 17 November 2023 (UTC)[reply]