Talk:Azacitidine

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Error in lead

There is a mistake on the page. 5-Aza and 5-Aza-2-Deoxycytidine are not the same drugs. The first words give this impression. —Preceding unsigned comment added by 80.141.163.49 (talk • contribs) 14:29, 3 October 2007

Fixed. Thank you for noticing. Fvasconcellos (t·c) 15:26, 3 October 2007 (UTC)[reply]

As far as I know, 5-Aza doesn't demthylate directly as it can be understood from the text. The methylation itself remains the same BUT in the process of cell division, the new alleles are no longer methylated leading in time to a decreased level of methylation. —Preceding unsigned comment added by 162.129.251.30 (talk) 20:23, 12 January 2010 (UTC)[reply]

I am confused by statements in this article regarding RNA methylation. My understanding is that Azacitidine affects tRNA methylation, and therefore may affect its folding and stability. This may lead to more general effects on translation. [Cancer Res 2009;69(20):8127–32]. The general statement on RNA methylation in this stub may not be clear enough. Bfeuerstein (talk) 01:24, 31 August 2010 (UTC)[reply]

Name

Is the name "azacytidine" or "azacitidine"?

Perhaps someone could mention this in the main article. If it is similar to cytidine for instance (or perhaps not, I don't know myself, hence why I asked here on the talk page). 2A02:8388:1600:A880:BE5F:F4FF:FECD:7CB2 (talk) 19:13, 15 February 2016 (UTC)[reply]

I had this question myself, since I'm about to be doing a bunch of work around this drug. It looks like both azacitidine and azacytidine are valid (among various others, see [1].) I personally prefer azacytidine, since the name is obviously derived from cytidine, but IIRC the naming policy is to stick with the original article title in the case of variants existing of the same name. -Kieran (talk) 19:50, 20 September 2016 (UTC)[reply]

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