Talk:Anthracycline

From WikiProjectMed
Jump to navigation Jump to search

Idarubicin structure

There is a mistake - idarubicin has no methoxy group at C-4 position (4-demethoxydaunorubicin). Please correct this mistake, because in these pictures there's no difference between daunorubicin and idarubicin.

Fixed here. Fvasconcellos (t·c) 18:28, 8 June 2008 (UTC)[reply]

Useful references

For future expansion: doi:10.1124/pr.56.2.6 doi:10.1124/mi.5.3.6 doi:10.1161/01.CIR.0000133187.74800.B9 Fvasconcellos (t·c) 18:28, 8 June 2008 (UTC)[reply]

doi:10.1124/pr.56.2.6 Anthracyclines: Molecular Advances and Pharmacologic Developments in Antitumor Activity and Cardiotoxicity
doi:10.1124/mi.5.3.6 The Cardiotoxicology of Anthracycline Chemotherapeutics: TRANSLATING MOLECULAR MECHANISM INTO PREVENTATIVE MEDICINE
doi:10.1161/01.CIR.0000133187.74800.B9 Cardiovascular Complications of Cancer Therapy

New ones in clinical trials

eg: In 2016 GPX-150 was granted Orphan Drug designation by US FDA.[1] - Rod57 (talk) 00:30, 11 February 2016 (UTC)[reply]

References

cardiotoxicity

I think it's classically described as decreased ejection fraction ultimately leading to dilated cardiomyopathy. — Preceding unsigned comment added by 99.228.106.37 (talk) 18:02, 31 August 2018 (UTC)[reply]